The Impact of CAROtid plaque Screening on Smoking (CAROSS) cessation and control of other cardiovascular risk factors: Rationale and design of a randomized controlled trial

Contemporary Clinical Trials
Nicolas RodondiJacques Cornuz

Abstract

Screening tests for subclinical cardiovascular disease, such as markers of atherosclerosis, are increasingly used in clinical prevention to identify individuals at high cardiovascular risk. Being aware of these test results might also enhance patient motivation to change unhealthy behaviors but the effectiveness of such a screening strategy has been poorly studied. The CAROtid plaque Screening trial on Smoking cessation (CAROSS) is a randomized controlled trial in 530 regular smokers aged 40-70 years to test the hypothesis that carotid plaque screening will influence smokers' behavior with an increased rate of smoking cessation (primary outcome) and an improved control of other cardiovascular risk factors (secondary outcomes) after 1-year follow-up. All smokers will receive a brief advice for smoking cessation,and will subsequently be randomly assigned to either the intervention group (with plaques screening) or the control group (without plaque screening). Carotid ultrasound will be conducted with a standard protocol. Smokers with at least one carotid plaque will receive pictures of their own plaques with a structured explanation on the general significance of plaques. To ensure equal contact conditions, smokers not undergoing...Continue Reading

Associated Clinical Trials

Oct 24, 2007·Nicolas Rodondi

References

Jul 11, 1991·Journal of General Internal Medicine·N A RigottiG E Thibault
Dec 1, 1983·Journal of Health and Social Behavior·S CohenR Mermelstein
Oct 23, 1997·The New England Journal of Medicine·R D HurtP M Sullivan
May 29, 1998·Circulation·P W WilsonW B Kannel
Apr 17, 2001·Annals of Internal Medicine·D G AltmanUNKNOWN CONSORT GROUP (Consolidated Standards of Reporting Trials)
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Oct 25, 2002·American Journal of Epidemiology·Diane E BildRussell P Tracy
May 8, 2003·JAMA : the Journal of the American Medical Association·Philip Greenland
Aug 11, 2004·Journal of Consulting and Clinical Psychology·Antonio Cepeda-BenitoStephen Erath
Nov 4, 2004·Cerebrovascular Diseases·P-J TouboulUNKNOWN Advisory Board of the 3rd Watching the Risk Symposium 2004, 13th European Stroke Conference
Dec 25, 2004·Diabetes Care·UNKNOWN American Diabetes Association
Mar 1, 2005·Tobacco Control·N D WeinsteinR P Moser
May 27, 2005·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN Centers for Disease Control and Prevention (CDC)
Jul 6, 2006·JAMA : the Journal of the American Medical Association·Douglas E JorenbyUNKNOWN Varenicline Phase 3 Study Group
Mar 8, 2008·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Nicolas RodondiJacques Cornuz

❮ Previous
Next ❯

Citations

Sep 2, 2011·Journal of General Internal Medicine·Nicolas RodondiJacques Cornuz
Jun 20, 2014·Journal of Evaluation in Clinical Practice·Sarah RonaldsonDavid Torgerson
Mar 29, 2008·American Heart Journal·David NanchenPascal Bovet
Nov 18, 2015·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Sarah ZinggNicolas Rodondi
Oct 19, 2012·The Cochrane Database of Systematic Reviews·Lasse T KrogsbøllPeter C Gøtzsche
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Raphaël BizeJacques Cornuz
Jan 22, 2010·The Cochrane Database of Systematic Reviews·Gareth J HollandsTheresa M Marteau
Jul 31, 2010·Current Opinion in Cardiology·Victor AboyansPhilippe Lacroix
Mar 27, 2019·The Cochrane Database of Systematic Reviews·Carole ClairRaphaël Bize

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Cardiovascular Risk Prediction

Cardiovascular risk prediction models based on classical risk factors identified in epidemiological studies are useful in primary prevention of cardiovascular disease in individuals. Here is the latest research.