The impact of chronic kidney disease on lower extremity bypass outcomes in patients with critical limb ischemia

Journal of Vascular Surgery
Vishnu AmburRavi Dhanisetty

Abstract

Patient selection for open lower extremity revascularization in patients with chronic kidney disease (CKD) remains a clinical challenge. This study investigates the impact of CKD on early graft failure, postoperative complications, and mortality in patients undergoing lower extremity bypass for critical limb ischemia. The National Surgical Quality Improvement Program database was queried for all patients with critical limb ischemia from 2012 to 2015 who underwent lower extremity bypass using the targeted vascular set. The glomerular filtration rate was calculated using the Chronic Kidney Disease Epidemiology Collaboration Study equation. CKD categories were determined from the National Kidney Foundation Kidney Disease Outcomes Quality Initiative staging criteria. Patients were classified into three groups: CKD stages 3 or lower (mild to moderate CKD), CKD stages 4 or 5 (severe CKD), and on hemodialysis (HD). Multiple variable analysis was used to examine graft failure, mortality, and postoperative complications. The Surgical Quality Improvement Program database identified 6978 patients who underwent infrainguinal lower extremity arterial bypass during the study period. There were 6101 patients (87.4%) with mild to moderate CKD,...Continue Reading

References

Sep 17, 1998·The New England Journal of Medicine·R G Luke
Oct 2, 2002·Annals of Internal Medicine·R Scott WrightAllan S Jaffe
Feb 26, 2008·Journal of Vascular Surgery·Niten SinghWilliam Henderson
Jun 10, 2010·Annals of Surgery·Karl Y BilimoriaClifford Y Ko
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Nov 19, 2013·Journal of Vascular Surgery·Prateek K GuptaK Craig Kent
Dec 3, 2014·Journal of Vascular Surgery·Karen C ChongS Marlene Grenon
Feb 27, 2017·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rajiv SaranVahakn Shahinian

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Citations

Feb 18, 2020·Circulation Journal : Official Journal of the Japanese Circulation Society·Shintaro ShibutaniUNKNOWN Japanese Bypass Registry Group, Tokyo, Japan
Jan 3, 2021·Journal of Vascular and Interventional Radiology : JVIR·John Di CapuaGregory T Walker
Jul 31, 2021·International Journal of General Medicine·Raffaele SerraMichele Andreucci

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