The impact of co-morbidity on health-related quality of life in breast cancer survivors and controls

Acta Oncologica
Dounya SchoormansYvonne Brandberg

Abstract

The objective of this study was: 1) to compare health-related quality of life (HRQoL) scores of breast cancer survivors to matched controls; and 2) to examine the relative impact (explained variance) of the type and number of co-morbidities on HRQoL. Data from the KARMA project was used in this cross-sectional study. For each woman diagnosed with breast cancer (n = 2552) there were two healthy age- and geographically matched females (n = 5104). Breast cancer survivors were categorized according to time since diagnosis: recently diagnosed (0-1 year), short- (2-5 years), mid- (6-10 years), and long-term survivors (> 10 years). Women completed a questionnaire addressing demographics (age, educational level, and geographical location), lifestyle factors (body mass index (BMI) and smoking), co-morbidities, and HRQoL. The difference in explained variance in six HRQoL-domains between demographics, lifestyle factors, and co-morbidity in women with breast cancer and matched controls was examined by hierarchical regression analyses. Women recently diagnosed (n = 63), reported the worst HRQoL followed by short-term survivors (2-5 years, n = 863). Thereafter, HRQoL scores further improved (6-10 years, n = 726), and were comparable to healt...Continue Reading

References

Jan 24, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D OsobaJ Pater
Jan 5, 2002·Journal of the National Cancer Institute·Patricia A GanzThomas R Belin
Dec 11, 2002·Archives of Physical Medicine and Rehabilitation·Robert M Kaplan
Dec 20, 2003·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M P ColemanUNKNOWN EUROCARE Working Group
Mar 17, 2004·Psycho-oncology·Joan R BloomPriscilla J Banks
Mar 22, 2005·The British Journal of Surgery·V E P P LemmensJ W W Coebergh
Jun 28, 2005·Critical Reviews in Oncology/hematology·Maryska L G Janssen-HeijnenJan Willem W Coebergh
Oct 18, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Floortje MolsLonneke V van de Poll-Franse
Oct 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Justin D FloydMichael C Perry
Sep 21, 2010·International Journal of Psychiatry in Medicine·Cherise B HarringtonMichael Feuerstein
Oct 12, 2010·International Journal of Radiation Oncology, Biology, Physics·Thomas WahlgrenYvonne Brandberg
Jun 19, 2012·Journal of Geriatric Oncology·Harvey Jay CohenAlice B Kornblith
Oct 12, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Arild André ØsthusHans J Aarstad
May 10, 2013·Breast Cancer Research and Treatment·Candyce H KroenkeLawrence H Kushi
Aug 7, 2013·Journal of Cancer Survivorship : Research and Practice·P A J VissersL V van de Poll-Franse
Aug 28, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tina HsuPamela J Goodwin

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Citations

Apr 25, 2015·Acta Oncologica·Christoffer Johansen, Susanne Oksbjerg Dalton
Nov 8, 2015·World Journal of Surgery·Megan K ApplewhiteBriseis Aschebrook-Kilfoy
Apr 25, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Clancy J ClarkJaime Bohl
Feb 9, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Vicki HartBrian L Sprague
Apr 29, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Mechelle D ClaridySelina A Smith
Dec 7, 2018·European Journal of Cancer Care·Michael FriedrichAndreas Hinz
Jan 25, 2020·Journal of the American Geriatrics Society·Yvonne L MichaelRowan T Chlebowski
Jun 18, 2019·The Cochrane Database of Systematic Reviews·Charlene J TreanorMichael Donnelly
Jul 28, 2019·Arthritis Care & Research·Elena LosinaJeffrey N Katz
Feb 12, 2019·European Journal of Cancer Care·Barbara MuzzattiMaria Antonietta Annunziata
Mar 13, 2020·Journal of Cancer Survivorship : Research and Practice·Jenny FirkinsNathan Dieckmann
Sep 18, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Maria Antonietta AnnunziataUmberto Tirelli
Jan 31, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Shannen R van der KrukTerry Boyle
Apr 6, 2021·Breast Cancer Research and Treatment·Angela ChetritSiegal Sadetzki

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