The Impact of Delivery in a Rural County on a Cohort of Women Living with HIV Infection and Their Infants

The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association
Gweneth B LazenbyDavid E Soper

Abstract

We sought to determine if infants born in rural counties had an increased risk of contracting HIV. Data were obtained from the South Carolina Department of Health and Environmental Control for all women living with HIV delivering from 2004 to 2014. In this retrospective cohort study, maternal and neonatal outcomes from urban and rural counties were compared. Binomial statistical analyses were conducted using Wilcoxon Rank Sum Tests, χ2 or Fisher's exact tests. Logistic regression analyses were performed to evaluate factors associated with perinatal HIV infection. Six hundred and sixty-six women living with HIV had 868 pregnancies and delivered 885 infants; 17% (148) were born in rural counties. Eleven infants (1.2%) were diagnosed with perinatal HIV infection. The proportion of women taking antenatal antiretroviral therapy (ART) was similar between rural and urban counties (84% vs 87%; P = .3), but women in urban counties were more likely to have an HIV RNA viral load <40 copies/mL before delivery (32% vs 42%; P = .05). Factors associated with perinatal HIV infection were intra- and postpartum maternal HIV diagnosis (aOR 61.4 [95% CI: 6.7-562.5]; P < .001), parenteral drug use (aOR 7.5 [1.6-34.7]; P = .01), and preterm birth (<...Continue Reading

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Citations

Jun 27, 2019·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Tyrone F Borders

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