The impact of dermatological toxicities of anti-cancer therapy on the dermatological quality of life of cancer patients

Journal of the European Academy of Dermatology and Venereology : JEADV
H S RaM R Roh

Abstract

One of the most common side effects of anti-cancer therapies is treatment-induced skin changes, referred to as dermatological toxicities. These dermatological toxicities are noteworthy since they have a negative association with quality of life (QoL). To evaluate the impact of dermatological toxicities on QoL of cancer patients and to identify the relationship between disease-related characteristics and QoL and changes in skin protective behaviours following anti-cancer therapy. Cancer patients (n = 80: stage II-IV) in a longitudinal prospective study completed a battery of questionnaires at the time of enrolment and after 3 months of anti-cancer therapy. QoL, skin toxicities, smoking and drinking behaviour, sun-protective and skin care behaviour assessments were performed before and at 3 months after anti-cancer therapy. QoL was measured with the Dermatology Life Quality Index (DLQI). A total of 73 patients completed the study. Among them, 48 patients (65.8%) experienced at least grade 1 skin toxicity at 3 months after anti-cancer therapy. Hair loss, hyperpigmentation and dry skin were the most common dermatological toxicities. The mean baseline DLQI score changed from 1.38 to 3.49 at 3 months after anti-cancer therapy. Domain...Continue Reading

References

May 1, 1994·Abdominal Imaging·P M SilvermanR K Zeman
May 1, 1994·Clinical and Experimental Dermatology·A Y Finlay, G K Khan
Sep 1, 1996·Clinical and Experimental Dermatology·G Kent, M al-Abadie
Feb 17, 2001·Psycho-oncology·J ZaboraS Piantadosi
Nov 13, 2001·The British Journal of Dermatology·C RenziM Braga
Feb 18, 2003·The British Journal of Dermatology·D ParsadB Kumar
Feb 18, 2004·Archives of Otolaryngology--head & Neck Surgery·John S RheeAnn B Nattinger
Nov 16, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mary WellsAlastair Munro
Sep 28, 2005·The Journal of Investigative Dermatology·Yan HongboAndrew Y Finlay
Dec 31, 2005·Journal of the American Academy of Dermatology·Sharon R HymesCaroline Fife
Mar 6, 2007·The Laryngoscope·John S RheeAnn B Nattinger
Jun 26, 2007·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jay Heidecker, Steven A Sahn
Aug 8, 2007·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Mark HackbarthJalid Sehouli
Jan 31, 2009·Indian Journal of Dermatology, Venereology and Leprology·Marjan DolatshahiMohsen Rezaei Hemami
Feb 1, 1994·Optics Letters·D PsaltisH Y Li
Mar 20, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·A Jin-gangW Xiao-peng
Mar 26, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ann Cameron HaleyMario E Lacouture
Nov 3, 2010·Pacing and Clinical Electrophysiology : PACE·William H SauerPaul D Varosy
Jan 7, 2011·Psychiatric Rehabilitation Journal·Jack TsaiAlan B McGuire

❮ Previous
Next ❯

Citations

Aug 3, 2014·Journal of the American Academy of Dermatology·Hagit BergmanGeoffrey Liu
Mar 21, 2016·Critical Reviews in Oncology/hematology·Cécile CharlesSarah Dauchy
Oct 7, 2016·Journal of Pharmaceutical Health Care and Sciences·Hidenobu TakahataIsao Adachi
Mar 2, 2019·Pediatric Blood & Cancer·Hannah SongJennifer T Huang
May 23, 2019·Current Drug Safety·Ciliberto DomenicoLuca Gallelli
Jan 13, 2016·Clinical Drug Investigation·Cécile CharlesCaroline Robert
Jan 8, 2020·International Journal of Women's Dermatology·Michelle N FerreiraJonathan S Leventhal
Mar 14, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Valencia LongChris Lixian Tan
Jun 25, 2021·Clinical, Cosmetic and Investigational Dermatology·Brigitte DrenoAndrew Alexis
Oct 9, 2021·Journal of Cutaneous Pathology·Riyad N H SeervaiJonathan L Curry
Apr 3, 2018·Asia-Pacific Journal of Oncology Nursing·Kaori YagasakiYasuo Hamamoto
Jul 12, 2017·Asia-Pacific Journal of Oncology Nursing·Andreas Charalambous

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.