The Impact of Developmental Timing for Stress and Recovery

Neurobiology of Stress
Dylan G Gee, B J Casey

Abstract

Stress can have lasting effects on the brain and behavior. Delineating the impact of stress on the developing brain is fundamental for understanding mechanisms through which stress induces persistent effects on behavior that can lead to psychopathology. The growing field of translational developmental neuroscience has revealed a significant role of the timing of stress on risk, resilience, and neuroplasticity. Studies of stress across species have provided essential insight into the mechanisms by which the brain changes and the timing of those changes on outcome. In this article, we review the neurobiological effects of stress and propose a model by which sensitive periods of neural development interact with stressful life events to affect plasticity and the effects of stress on functional outcomes. We then highlight how early-life stress can alter the course of brain development. Finally, we examine mechanisms of buffering against early-life stress that may promote resilience and positive outcomes. The findings are discussed in the context of implications for early identification of risk and resilience factors and development of novel interventions that target the biological state of the developing brain to ultimately ameliora...Continue Reading

References

May 1, 1987·Journal of Neuropathology and Experimental Neurology·B A BrodyF H Gilles
Apr 1, 1995·Current Opinion in Neurobiology·B S McEwen, R M Sapolsky
Jan 1, 1995·Neuroscience and Biobehavioral Reviews·S FeldmanJ Weidenfeld
Jun 1, 1994·Acta Paediatrica. Supplement·M A Hofer
Feb 12, 1998·Proceedings of the National Academy of Sciences of the United States of America·A M MagariñosB S McEwen
Jun 17, 1998·Endocrine Reviews·E R De KloetM Joëls
Apr 15, 1999·Annual Review of Neuroscience·B S McEwen
Feb 24, 2001·Development and Psychopathology·M R GunnarH D Grotevant
Dec 26, 2001·Psychoneuroendocrinology·Megan R Gunnar, Bonny Donzella
Mar 20, 2003·Biological Psychiatry·Ahmad R HaririDaniel R Weinberger
Mar 6, 2004·Annals of the New York Academy of Sciences·Barbara Olasov Rothbaum, Michael Davis
May 19, 2004·Proceedings of the National Academy of Sciences of the United States of America·Nitin GogtayPaul M Thompson
Jul 22, 2004·Journal of Neurobiology·Susan C Cook, Cara L Wellman
Sep 8, 2004·Archives of General Psychiatry·Karen J ParkerDavid M Lyons
Apr 12, 2005·Biological Psychiatry·Karen J ParkerDavid M Lyons
May 28, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Paul M PlotskyMichael J Meaney
Jun 17, 2005·The New England Journal of Medicine·Ronald C KesslerAlan M Zaslavsky
Jun 22, 2005·Proceedings of the National Academy of Sciences of the United States of America·Rupshi MitraSumantra Chattarji
Aug 16, 2005·Neuroscience and Biobehavioral Reviews·Robert E AdamecPaul Burton
Jun 3, 2006·The American Journal of Psychiatry·Martin H TeicherCynthia E McGreenery
Jun 24, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adriana GalvanB J Casey
Jul 11, 2006·Nature Neuroscience·Stephanie Moriceau, Regina M Sullivan
Jul 28, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Conor ListonBruce S McEwen
Dec 15, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jason J RadleyPaul E Sawchenko
Dec 22, 2006·Developmental Science·Barbara L Finlay
Mar 23, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael J SabatiniKároly Mirnics
Aug 19, 2007·Nature Neuroscience·Hai-Yan HeElizabeth M Quinlan
Apr 19, 2008·Science·José Fernando Maya VetencourtLamberto Maffei
Jun 21, 2008·Endocrinology·Courtney J RiceTallie Z Baram
Oct 8, 2008·Development and Psychopathology·Christopher S Monk
Nov 6, 2008·Social Cognitive and Affective Neuroscience·Sarah J BanksK Luan Phan

❮ Previous
Next ❯

Citations

Aug 8, 2015·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Anthony S ZannasElisabeth B Binder
Apr 9, 2016·Neural Plasticity·Laura Musazzi, Jordan Marrocco
May 14, 2016·Developmental Cognitive Neuroscience·Dominic S Fareri, Nim Tottenham
Jul 16, 2016·Experimental Neurology·Sarah R HornAdriana Feder
Oct 22, 2016·Neuroscience and Biobehavioral Reviews·Nim Tottenham, Adriana Galván
Sep 3, 2016·New Directions for Child and Adolescent Development·Dylan G Gee
Oct 16, 2016·Development and Psychopathology·Allison N MacdonaldElaine F Walker
Jan 21, 2017·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Camelia E HostinarGregory E Miller
Jul 8, 2017·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Heidi C MeyerDylan G Gee
Sep 6, 2017·Scientific Reports·Milla K AholaHannes Lohi
Apr 27, 2019·PloS One·Sarah R HornPhilip A Fisher
Dec 24, 2019·The Journal of Neuropsychiatry and Clinical Neurosciences·Liat LevitaMarkus Reuber
Jul 11, 2019·Archives of Women's Mental Health·Crystal Modde EpsteinCarol H Pullen
Jul 24, 2018·Environmental Epigenetics·Olivia Engmann
Sep 6, 2019·Clinical Psychological Science : a Journal of the Association for Psychological Science·Theodore P BeauchaineJeffrey A Bridge
Jun 18, 2017·Frontiers in Neurology·Tore Nielsen
May 8, 2018·Harvard Review of Psychiatry·Sarah R Horn, Adriana Feder
Sep 11, 2019·Cerebral Cortex·Maximilian MonningerNathalie E Holz
Oct 6, 2020·Brain and Neuroscience Advances·Nichola M Brydges, Jack Reddaway
Dec 16, 2017·Psychodynamic Psychiatry·Regina M Sullivan
Jan 30, 2020·Stress and Health : Journal of the International Society for the Investigation of Stress·Teresa SmithGeorge M Slavich
Jun 6, 2020·Frontiers in Psychiatry·Monica MazzelliNadia Cattane
May 16, 2017·European Child & Adolescent Psychiatry·Jaume March-LlanesJorge Moya-Higueras
Oct 23, 2020·Developmental Science·Emma Chad-FriedmanLea R Dougherty
Nov 28, 2020·Social Cognitive and Affective Neuroscience·Karolina I RokitaGary Donohoe
Dec 17, 2020·Developmental Psychobiology·May I ConleyB J Casey
Dec 30, 2020·Epigenetics : Official Journal of the DNA Methylation Society·Radhika KandaswamyChloe C Y Wong
Jan 8, 2021·Research on Child and Adolescent Psychopathology·Emily M CohodesDylan G Gee
Aug 19, 2020·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Dylan G Gee
Sep 10, 2020·Current Opinion in Behavioral Sciences·Kristina Woodard, Seth D Pollak

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Related Papers

The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine
Tim F Oberlander
Frontiers in Behavioral Neuroscience
Gang WuAleksander A Mathé
© 2021 Meta ULC. All rights reserved