PMID: 9181643Jan 1, 1997Paper

The impact of exposure group on the progression rate to acquired immunodeficiency syndrome. A comparison between intravenous drug users, homosexual men and heterosexually infected subjects

Scandinavian Journal of Infectious Diseases
A EskildL S Bakketeig

Abstract

The objective was to study the impact of exposure group on the progression rate to the acquired immunodeficiency syndrome (AIDS). 289 subjects in Oslo, Norway, infected with the human immunodeficiency syndrome (HIV) and without major clinical signs of HIV infection (102 intravenous drug users, 151 homosexual men and 36 heterosexually infected subjects) were recruited to the Oslo HIV Cohort Study from 1989 and followed until 1 January 1995. 15 (14.7%) of the intravenous drug users, 56 (37.1%) of the homosexual men and 5 (12.5%) of the heterosexually infected subjects developed AIDS during a mean time of 47 months (p < 0.001, log rank test). When controlling for possible confounding variables (age, number of CD4+ lymphocytes, antiviral therapy at study entry, gender and year of HIV diagnosis), the relative risk of AIDS progression was 2.2 [1.1-4.5, 95% confidence interval (CI)] for homosexual men and 0.5 (0.2-1.3, 95% CI) for heterosexually infected subjects as compared to intravenous drug users. In a subgroup with known time of seroconversion (n = 60), 47% (18/38) of the homosexual men, 20% (3/15) of the intravenous users and none (0/7) of the heterosexually infected subjects developed AIDS (p = 0.04, log rank test). The results...Continue Reading

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Citations

Dec 12, 2001·HIV Medicine·UNKNOWN CASCADE (Concerted Action on SeroConversion to AIDS and Death in Europe) Collaboration
Dec 4, 2010·Occupational Medicine·F D DickUNKNOWN Guideline Development Group
Feb 25, 2003·Current Opinion in Rheumatology·Till UhligTore K Kvien
Jan 11, 2002·The Clinical Journal of Pain·W R Nielson, R Weir
Feb 13, 2007·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Jan-Rickard NorrefalkKristian Borg
May 17, 2011·PloS One·Patricia Ribeiro Dos SantosCécile Butor
Mar 1, 2011·Journal of Substance Abuse Treatment·Aaron M KippHan-Zhu Qian
May 19, 2000·Scandinavian Journal of Public Health·A SkrondalJ Thorvaldsen
Apr 1, 1998·Journal of Health Psychology·O Vassend, A Eskild
Mar 31, 2017·The Cochrane Database of Systematic Reviews·Nicole VogelRegina Kunz

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