The impact of FDG-PET/CT in the management of patients with vulvar and vaginal cancer

Gynecologic Oncology
N L RobertsonH A Vargas

Abstract

To evaluate the changes in prognostic impression and patient management following PET/CT in patients with vulvar and vaginal carcinoma; and to compare PET/CT findings with those of conventional imaging modalities. We summarized prospectively and retrospectively collected data for 50 consecutive patients from our institution that enrolled in the National Oncologic PET Registry and underwent FDG-PET/CT for a suspected or known primary or recurrent vulvar/vaginal cancer. 54/83 (65%) studies included had a diagnosis of vulvar cancer, and the remaining 29/83 (35%), a diagnosis of vaginal cancer. Following FDG-PET/CT, the physician's prognostic impression changed in 51% of cases. A change in patient management, defined as a change to/from a non-interventional strategy (observation or additional imaging), to/from an interventional strategy (biopsy or treatment), was documented in 36% of studies. The electronic records demonstrated that 95% of the management strategies recorded in the physician questionnaires were implemented as planned. MRI and/or CT were performed within one month of the FDG-PET/CT in 20/83 (24%) and 28/83 (34%) cases, respectively. FDG-PET/CT detected nodes suspicious for metastases on 29/83 (35%) studies performed....Continue Reading

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Citations

Oct 12, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Linda J Rogers, Mauricio A Cuello
Jan 9, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Mikel GorostidiGlauco Baiocchi
May 18, 2016·Clinical Nuclear Medicine·Darshan PatelYang Lu
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Feb 24, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Vittoria RufiniAngela Collarino
Mar 7, 2020·The Lancet Oncology·Henrike WesterveldRemi A Nout
Feb 26, 2021·Clinical Nuclear Medicine·Kgomotso M G MokoalaMike M Sathekge
May 1, 2021·Revista española de medicina nuclear e imagen molecular·A YanarateşB Yazici
May 8, 2021·Journal of the American College of Radiology : JACR·UNKNOWN Expert Panel on GYN and OB ImagingPhyllis Glanc
Jul 18, 2021·Japanese Journal of Radiology·Domenico AlbanoFrancesco Bertagna
Aug 3, 2021·Abdominal Radiology·Rachel SteinChandana Lall
Aug 17, 2021·Radiologic Clinics of North America·Saul N FriedmanFarrokh Dehdashti
Aug 27, 2021·Abdominal Radiology·Lucy ChowMaitraya K Patel

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