The impact of frailty on noninvasive mechanical ventilation in elderly medical intensive care unit patients

Aging Clinical and Experimental Research
Iskender KaraG Gursel

Abstract

Many factors affecting noninvasive ventilation (NIV) in critically ill patients have been reported in the literature, but there is no study about the effect of frailty. With this study, the frailty prevalence was evaluated with two different frailty scores among the NIV population of a medical intensive care unit (ICU). Besides, the impact of frailty on NIV success and mortality and its association with NIV application problems were evaluated. A prospective observational cohort study was performed on patients who were over 50 years of age and assigned to NIV due to hypercapnic respiratory failure. For the assessment of frailty, Clinical Frailty Scale (CFS) and The Edmonton Frailty Scale (EFS) were used and the ones with CFS ≥5 and EFS ≥8 were considered as fragile. The study population was classified and compared according to NIV success, ICU outcome (discharge or exitus) and NIV application problems. A total of 103 patients with the mean age of 73 ± 11 years were included. The incidence of frailty was 41% with CFS ≥5 and 36% with EFS ≥8. The NIV failure occurred in 30 (29%) patients. Among them frailty and SOFA score was higher; Glasgow Coma Scale (GCS) was lower. In multivariate analysis GCS (OR: 1.2, p: 0.042) and frailty wi...Continue Reading

References

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Citations

Aug 16, 2017·Aging Clinical and Experimental Research·Iskender KaraGul Gursel
Aug 16, 2017·Aging Clinical and Experimental Research·Nicola Vargas, Antonio M Esquinas
May 10, 2020·Anesthesia and Analgesia·Justin C De BiasioShahzad Shaefi
Apr 22, 2021·Archives of Gerontology and Geriatrics·Alberto PilottoUNKNOWN Italian Geriatric Society Hospital and Community (SIGOT) Study Group

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