The impact of hyaluronan-enriched culture medium and intrauterine infusion of human chorionic gonadotropin on clinical outcomes in blastocyst transfer cycles

Systems Biology in Reproductive Medicine
Hanna BalakierClifford L Librach

Abstract

Over the last few decades, advances in ovarian hormonal stimulation, embryology laboratory technologies and embryo genetic testing, have significantly enhanced clinical outcomes in human assisted reproduction technologies (ART). However, embryo implantation remains a major bottleneck in achieving better pregnancy and live birth rates. Thus, there is growing interest in establishing new approaches to enhance implantation efficiency after embryo transfer. With advanced molecular techniques, many promising biomarkers associated with embryonic and endometrial changes occurring prior to and during embryo implantation have been identified. However, despite the progress in applying novel procedures into IVF practice, clinical evaluation of those biomarkers has so far reached modest predictive value for enhancing blastocyst developmental potential and endometrial receptivity. Therefore, other simpler strategies have also been introduced to increase the rates of successful clinical pregnancies and live births. One of these approaches is to investigate the impact of using embryo transfer medium containing high concentrations of an adherence compound, such as hyaluronic acid (HA), on IVF outcomes. Additionally, intrauterine infusion of a ...Continue Reading

References

Jun 29, 1984·Biochemical and Biophysical Research Communications·E Turley, D Moore
Feb 1, 1995·Human Reproduction·S CampbellM Elstein
Aug 1, 1995·Human Pathology·N YaegashiM Nakamura
Jun 1, 1997·Molecular Human Reproduction·A LopataD M Robertson
Jan 17, 2002·The New England Journal of Medicine·E R NorwitzS J Fisher
Oct 29, 2003·Theriogenology·Cecilia C FurnusAna Lía Errecalde
Nov 1, 2006·Fertility and Sterility·Kalliopi E LoutradiBasil C Tarlatzis
Nov 4, 2006·Molecular and Cellular Endocrinology·Laurence A Cole, Sarah A Khanlian
Mar 3, 2007·Contemporary Clinical Trials·Caroline TournouxBernard Asselain
Sep 4, 2007·Fertility and Sterility·William David HazlettVishvanath C Karande
Oct 19, 2007·The Cochrane Database of Systematic Reviews·D A BlakeM Proctor
Dec 8, 2007·Reproductive Biomedicine Online·Sara KorosecHelena Meden-Vrtovec
Oct 23, 2008·Journal of Assisted Reproduction and Genetics·Arthur BabayanSteven S Witkin
Jun 30, 2009·Journal of Human Reproductive Sciences·Ann M MangalrajKorula George
Aug 26, 2010·Reproductive Biology and Endocrinology : RB&E·Laurence A Cole
Feb 5, 2011·NASN School Nurse·Laura B SmithUNKNOWN National Diabetes Education Program
Oct 27, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Laurence A Cole
Mar 30, 2012·Reproductive Biology and Endocrinology : RB&E·Laurence A Cole
Apr 25, 2012·Journal of Assisted Reproduction and Genetics·Koji NakagawaRikikazu Sugiyama
Jun 12, 2012·Biochimica Et Biophysica Acta·Y E M KootN S Macklon
Jan 8, 2013·Molecular Aspects of Medicine·Shuang ZhangD Randall Armant
Feb 26, 2014·The Cochrane Database of Systematic Reviews·Stephan BontekoeDebbie Blake
May 3, 2014·Fertility and Sterility·Evan M RosenbluthBradley J Van Voorhis
May 21, 2014·Fertility and Sterility·Bruce S ShapiroCynthia Hudson
Jun 12, 2014·Human Reproduction Update·Jemma EvansLuk J F Rombauts
Nov 16, 2014·Archives of Gynecology and Obstetrics·Peter FancsovitsJanos Urbancsek
Nov 28, 2014·Journal of Assisted Reproduction and Genetics·Matheus Roque
Mar 4, 2015·Seminars in Reproductive Medicine·Jason E Swain

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