The impact of maternal age on pregnancy and its outcome

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
M MilnerR F Harrison


There were 28,600 deliveries of 500 g or more to women at the Rotunda Hospital between January 1st 1985 and December 1st 1989. Of these, 595 were to women aged 40 years and over. Thirty-five variables of clinical significance were analyzed, comparing those of 40 years of age and more with those under 40. The older group had significant increases in gestational diabetes, ante-partum hemorrhage, fetal distress, prematurity, low birth weight and perinatal mortality. Chromosome congenital abnormalities were significantly higher, particularly Down syndrome. There were significantly increased rates of induction and cesarean section in the older women. Some evidence of interaction of age with other factors was found, however these were difficult to separate out in the clinical setting. We therefore recommend it wiser to manage all elderly gravidas in a high risk manner dealing with cases individually within this framework. Intervention should, however, need to be justified in the older as in the younger woman.


Mar 2, 1991·Lancet·P A BairdI M Yee
Sep 1, 1990·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·D S SeidmanJ G Schenker
Jun 8, 1991·BMJ : British Medical Journal·B M van Noord-ZaadstraJ Karbaat
Mar 8, 1990·The New England Journal of Medicine·G S BerkowitzR L Berkowitz
Aug 9, 1990·The New England Journal of Medicine
Feb 1, 1990·Obstetrical & Gynecological Survey·D Hollander, J L Breen
Jan 1, 1989·Health Care for Women International·P K Mansfield, W McCool
Apr 1, 1989·American Journal of Obstetrics and Gynecology·H Shapiro, E Lyons
Nov 1, 1986·Obstetrical & Gynecological Survey·J P Hansen
Dec 1, 1988·Obstetrical & Gynecological Survey·V J Fonteyn, N B Isada
Jan 1, 1988·Maturitas·W H Utian, R Kiwi
Mar 1, 1988·British Journal of Obstetrics and Gynaecology·S M TuckA C Turnbull
May 1, 1985·American Journal of Obstetrics and Gynecology·D S KirzR K Freeman

❮ Previous
Next ❯


Jul 1, 1993·Journal of Assisted Reproduction and Genetics·A Benshushan, J G Schenker
Dec 20, 2003·Archives of Gynecology and Obstetrics·Hamisu M SalihuGreg R Alexander
Feb 1, 2008·Archives of Gynecology and Obstetrics·Muktar H AliyuRussell S Kirby
Oct 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y EzraD Farine
Dec 16, 2003·Obstetrics and Gynecology·Hamisu M SalihuGreg R Alexander
Dec 10, 1998·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H KarroA Baburin
Oct 11, 2005·Health Care for Women International·Christine V Newburn-Cook, Judee E Onyskiw
Jan 16, 1999·The Australian & New Zealand Journal of Obstetrics & Gynaecology·S F Wong, L C Ho
Sep 14, 2004·Gynecologic and Obstetric Investigation·F J Broekmans, E R Klinkert
Dec 25, 2013·BMC Pregnancy and Childbirth·Andrew H MgayaHans N Mgaya
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M PrasadH Al-Taher
Oct 10, 2001·Human Fertility : Journal of the British Fertility Society·D Nugent, A H Balen
Feb 7, 2003·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Mary Carolan
Mar 15, 2005·Acta Obstetricia Et Gynecologica Scandinavica·Hamisu M SalihuGreg R Alexander
Oct 7, 2008·The Journal of Obstetrics and Gynaecology Research·Hamisu M SalihuRussell S Kirby
Feb 24, 2011·Pediatrics International : Official Journal of the Japan Pediatric Society·Mariko IwayamaToshiro Hara
Aug 17, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·H R MurphyUNKNOWN East Anglia Study Group for Improving Pregnancy Outcomes in Women with Diabetes (EASIPOD)
Jan 20, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·R BakkerV W V Jaddoe
Feb 26, 2004·American Journal of Obstetrics and Gynecology·Hamisu M SalihuGreg R Alexander
Jun 3, 1999·Birth·K C Windridge, J C Berryman
Jan 19, 2012·Korean journal of pediatrics·Jae Woo Lim
Sep 2, 2005·Obstetrics and Gynecology·Sara M Ellis SimonsenMichael W Varner
Jan 15, 2002·The Australian & New Zealand Journal of Obstetrics & Gynaecology·P A Kraus, S Hassan
May 12, 2005·American Journal of Medical Genetics. Part a·Hamisu M SalihuRussell S Kirby
Mar 19, 2004·Journal of Perinatology : Official Journal of the California Perinatal Association·Hind BeydounUNKNOWN National Collaborative Perinatal Neonatal Network
Dec 1, 1994·Developmental Medicine and Child Neurology·J M Davies, J G Jenkins
Oct 8, 2009·The Journal of Clinical Endocrinology and Metabolism·Montserrat BalsellsR Corcoy

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Obstetrics, Gynecology, and Reproductive Biology
P VercelliniA Cardinale
Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
M PrasadH Al-Taher
American Journal of Perinatology
Muhieddine A-F SeoudAli M Khalil
European Journal of Obstetrics, Gynecology, and Reproductive Biology
H NarayanJ Cullimore
Obstetrics and Gynecology
A BiancoR L Berkowitz
© 2022 Meta ULC. All rights reserved