The impact of maternal gestational weight gain on cardiometabolic risk factors in children

Diabetologia
Claudia H T TamWing Hung Tam

Abstract

Accumulating evidence suggests an impact of gestational weight gain (GWG) on pregnancy outcomes; however, data on cardiometabolic risk factors later in life have not been comprehensively studied. This study aimed to evaluate the relationship between GWG and cardiometabolic risk in offspring aged 7 years. We included a total of 905 mother-child pairs who enrolled in the follow-up visit of the multicentre Hyperglycemia and Adverse Pregnancy Outcome study, at the Hong Kong Centre. Women were classified as having gained weight below, within or exceeding the 2009 Institute of Medicine (IOM) guidelines. A standardised GWG according to pre-pregnancy BMI categories was calculated to explore for any quadratic relationship. Independent of pre-pregnancy BMI, gestational hyperglycaemia and other confounders, women who gained more weight than the IOM recommendations had offspring with a larger body size and increased odds of adiposity, hypertension and insulin resistance (range of p values of all the traits: 4.6 × 10-9 < p < 0.0390) than women who were within the recommended range of weight gain during pregnancy. Meanwhile, women who gained less weight than outlined in the recommendations had offspring with increased risks of hypertension a...Continue Reading

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Citations

Apr 24, 2020·Journal of Public Health·Camila Honorato A TorresMarco F Mastroeni
Jun 23, 2020·Maternal & Child Nutrition·Szimonetta EitmannErika Pétervári
Sep 8, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Fionnuala M McAuliffeMoshe Hod
Jul 28, 2020·International Journal of Obesity Supplements·Alessandra GambineriUNKNOWN Obesity Programs of nutrition, Education, Research and Assessment (OPERA) Group
Jun 15, 2019·Obesity·Catherine O BuckJoseph M Braun
Jul 28, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Stephanie PirottaLeah Brennan
Feb 26, 2021·Stroke; a Journal of Cerebral Circulation·Milja KiveläMarkus Paananen
May 6, 2021·International Journal of Molecular Sciences·Purificación RosJulie A Chowen
Aug 17, 2021·Therapeutic Advances in Reproductive Health·Mahnaz Bahri KhomamiLisa J Moran
Jan 6, 2022·Fundamental & Clinical Pharmacology·Sergio De Los SantosPatricia Canto
Jan 19, 2022·Paediatric and Perinatal Epidemiology·Szimonetta EitmannErika Pétervári

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