The impact of mental workload on inhibitory control subprocesses

NeuroImage
Witold X ChmielewskiChristian Beste

Abstract

The inhibition of inappropriate responses is a function known to rely on prefrontal cortex (PFC) functioning. Similarly, working memory processes are known to rely on the PFC. Even though these processes are usually closely intertwined and the functional neuroanatomy underlying these processes is largely overlapping, the influence of working memory load on inhibitory control process has remained largely elusive. In the current study, we therefore examine how response inhibition processes are modulated by working memory load. For this, we systematically increased the working memory load of participants by integrating mental rotation processes in a Go/NoGo paradigm. To examine the system neurophysiology of these processes in detail, and to examine whether there are differential effects of working memory load on distinct response inhibition subprocesses, we applied event-related potentials (ERPs) in combination with source localization techniques. The data shows that after exceeding a certain threshold, inhibitory control processes are aggravated by working memory load. The neurophysiological data paralleled the behavioral data. However, it suggests that distinguishable response inhibition subprocesses are differentially modulated...Continue Reading

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Citations

Jul 2, 2015·Archives of Toxicology·Ann-Kathrin StockChristian Beste
Jun 6, 2019·Journal of Neurophysiology·Nico AdelhöferChristian Beste
Oct 28, 2019·Human Brain Mapping·Julia Friedrich, Christian Beste
Nov 6, 2018·Frontiers in Neuroscience·Jingting LiHanjun Liu
Mar 13, 2021·NeuroImage. Clinical·Nico AdelhöferChristian Beste
Jul 8, 2021·Journal of Neurophysiology·Astrid ProchnowChristian Beste
Sep 8, 2021·Experimental Brain Research·Zhuyun ZhangHeming Gao

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