The Impact of Micropapillary Component Ratio on the Prognosis of Patients With Invasive Micropapillary Breast Carcinoma

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
Cemal KayaMehmet Mihmanlı

Abstract

Invasive micropapillary carcinoma (IMPC) of the breast is a rare and aggressive variant of invasive ductal carcinoma characterized by high-grade lymphovascular invasion and high rates of nodal metastasis. The prognostic significance of the micropapillary component (MC) ratio that constitutes this aggressive variation is controversial. In this study, we aimed to investigate the effect of the MC ratio on the prognosis of these patients. The data of 47 patients with IMPC were retrospectively reviewed. Patients were divided into two groups: MC ratio of 10-75% (Group 1) and greater than 75% (Group 2). The demographic characteristics of the patients, histopathologic features of the tumors, and survival rates were compared. We detected no significant difference in demographic characteristics between groups 1 and 2 (p = 0.21). No significant difference was detected in terms of tumor diameter, lymph node metastasis, lymphovascular invasion, histologic grade, multicentricity, local recurrence, distant metastasis, and overall survival. In the micropapillary subgroup of invasive ductal carcinoma, although positive receptor characteristics are directly proportional to the increase in MC ratio, recurrence and survival rates are not affected ...Continue Reading

References

Feb 10, 2000·Human Pathology·M PaterakosA D Thor
Sep 15, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·H NassarD Visscher
Jan 15, 2004·Pathology International·Clarissa De la CruzHironobu Sasano
Nov 20, 2004·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Hajime KurodaShinji Itoyama
Dec 13, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Antonio C WolffUNKNOWN College of American Pathologists
Apr 18, 2008·International Journal of Surgical Pathology·Ling ChenLi Fu
Feb 25, 2009·The American Journal of Surgical Pathology·Tamara L LotanJonathan I Epstein
Nov 28, 2009·Nature Reviews. Clinical Oncology·Britta Weigelt, Jorge S Reis-Filho
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Apr 21, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M Elizabeth H HammondAntonio C Wolff
May 7, 2010·Japanese Journal of Clinical Oncology·Rin YamaguchiHirohisa Yano
Jun 29, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A GoldhirschUNKNOWN Panel members
Nov 2, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Bibhusal ThapaGita Sayami
Jun 15, 2014·Breast Cancer Research and Treatment·Francisco E Vera-BadilloEitan Amir
Aug 15, 2014·Journal of the National Cancer Institute·William F AndersonMark E Sherman

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