The impact of microwave-assisted organic synthesis in drug discovery

Drug Discovery Today
Farah Mavandadi, Ake Pilotti

Abstract

Microwave-assisted organic synthesis has revolutionized organic synthesis. Small molecules can be built in a fraction of the time required by classical thermal methods. As a result, this technique has rapidly gained acceptance as a valuable tool for accelerating drug discovery and development processes. This article outlines the basic principles behind microwave technology and summarizes recent trends and areas in drug discovery where this technology has made an impact.

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Citations

Jul 3, 2013·European Journal of Medicinal Chemistry·Enrique TorresSilvia Pérez-Silanes
Apr 21, 2011·Journal of Medicinal Chemistry·Stephen D Roughley, Allan M Jordan
Feb 26, 2014·International Journal of Molecular Sciences·M Pilar Vázquez-TatoJulio A Seijas
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Apr 1, 2016·Chemical Science·Raúl Díaz-TorresNúria Aliaga-Alcalde
Apr 22, 2009·Molecular Diversity·C Oliver Kappe, Doris Dallinger
Feb 10, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ghadah AljohaniAdeeb Al-Sheikh Ali
Sep 1, 2007·Journal of Combinatorial Chemistry·Xia-Min Cheng, Xue-Wei Liu
Dec 5, 2008·Journal of Combinatorial Chemistry·Carmen Gil, Stefan Bräse
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Dec 2, 2017·The Journal of Organic Chemistry·Mélanie BollierNatascha Leleu-Chavain
May 19, 2018·The Journal of Organic Chemistry·Junior GonzalesCharles Michael Drain

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