The impact of migraine on patients with major depressive disorder

Headache
Ching-I HungShuu-Jiun Wang

Abstract

The impact of migraine and other headache types among psychiatric outpatients with major depressive disorder (MDD) has not been fully described. To investigate the impact of migraine on the severity, physical, and anxiety symptoms in patients with MDD and to examine the interaction between headache and depression. This clinic-based study enrolled consecutive psychiatric outpatients meeting DSM-IV criteria for MDD. Headache types were diagnosed based on the International Classification of Headache Disorders, 2nd edition (2004). Three psychometric instruments were used to evaluate anxiety, depression, and physical components: the Hamilton Depression Rating Scale, the Beck Depression Inventory, and the Hospital Anxiety and Depression Scale. In addition, the interactions between headache and their depressive episode were also evaluated. Compared with patients without migraine, MDD patients with comorbid migraine (n = 73, 48.3%) had higher physical and anxiety scores on the three psychometric instruments. Migraine accounted for 5% to 11% of the variance of the total scores on the three psychometric scales. Approximately half (48.5%) of patients reported headache worsening during or after a depressive episode. Our study found that co...Continue Reading

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Citations

Oct 30, 2008·Journal of Neurology·H C DienerT Kurth
Aug 2, 2008·Clinical Neuropharmacology·Vasilios G MasdrakisConstantin R Soldatos
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Apr 10, 2013·The Journal of Headache and Pain·Ching-I HungShuu-Jiun Wang
Jun 20, 2020·Journal of Affective Disorders·Dong Hyun LeeMin Kyung Chu

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