The impact of mobile applications on medication adherence: a systematic review.

Translational Behavioral Medicine
Ricki NgSarira El-Den

Abstract

In 2008, Apple and Android launched their Application or "App" stores. Since then, there has been a growing interest in using mobile apps for improving medication adherence. However, research on the efficacy of apps, in terms of improved medication adherence and clinical outcome and/or patient-related outcome measures (PROMs) is scarce. The objective of this research was to systematically review the impact of apps on consumers' medication adherence and to determine the effect on clinical outcome and/or PROM(s). A systematic literature search was conducted to identify publications aimed at improving medication adherence published from January 2008 to April 2018. All studies were assessed for risk of bias using either the Risk Of Bias In Non-randomized Studies-of Interventions or the revised tool for Risk of Bias in randomized trials tool, depending on study design. Eleven randomized controlled trials (RCTs) and 10 non-RCTs were included. All 11 RCTs showed improvements in adherence; however, only seven reported statistically significant improvements in at least one adherence measure. Nine RCTs also demonstrated improvements in clinical outcome/PROM(s), of which five were statistically significant, whereas two RCTs did not report...Continue Reading

References

Jan 18, 2005·International Journal for Equity in Health·Abdesslam Boutayeb, Saber Boutayeb
Nov 6, 2007·The Medical Journal of Australia·Bruce K ArmstrongLesley M Russell
Dec 9, 2008·British Journal of Nursing : BJN·Danny Meetoo
Feb 20, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Lidwine B MokkinkHenrica C W de Vet
Aug 19, 2011·International Journal of Clinical Practice·W W ChongT F Chen
Nov 2, 2011·Oman Medical Journal·Beena Jimmy, Jimmy Jose
Jan 8, 2013·Journal of Medical Internet Research·Kathryn E MuessigLisa B Hightow-Weidman
Jan 18, 2013·European Journal of Gastroenterology & Hepatology·Kevin A HommelLee A Denson
Apr 2, 2013·Best Practice & Research. Clinical Obstetrics & Gynaecology·Bruno Lunenfeld, Pamela Stratton
Apr 11, 2013·Journal of the American Pharmacists Association : JAPhA·Lindsey DayerBradley C Martin
Jul 23, 2013·Patient Preference and Adherence·Jacqueline G HugtenburgLiset van Dijk
Apr 8, 2014·Journal of Medical Internet Research·José Joaquín MiraNuria Toro
Jun 25, 2014·Journal of Telemedicine and Telecare·Carly M GoldsteinJoel W Hughes
Oct 23, 2014·Journal of American College Health : J of ACH·Tracy HammondsJoel W Hughes
Dec 5, 2014·International Journal of Clinical Practice·H Anglada-MartinezC Codina-Jane
Mar 19, 2015·Annual Review of Public Health·Amanda K HallJay M Bernhardt
Mar 25, 2015·Journal of Medical Internet Research·Saee HamineAmy Sarah Ginsburg
May 15, 2015·JMIR MHealth and UHealth·Martin F MendiolaSarah Lindenauer
Sep 24, 2015·Methods of Information in Medicine·E AmmenwerthG Poelzl
Sep 24, 2015·Patient Preference and Adherence·Elísio CostaAlessandra Marengoni
Nov 6, 2015·BioMed Research International·Wai Yin Lam, Paula Fresco
Dec 2, 2015·Translational Behavioral Medicine·Michael J StirrattWendy J Nilsen
Dec 15, 2015·Journal of the American Medical Informatics Association : JAMIA·Kevin B JohnsonShelagh A Mulvaney
Feb 7, 2016·The Lancet. Psychiatry·John Torous, Joseph Firth
Apr 15, 2016·Nature·Emily Anthes
Aug 5, 2016·Asia Pacific Allergy·Mi-Yeong KimYoon-Seok Chang
Aug 16, 2016·Patient Preference and Adherence·William H Polonsky, Robert R Henry
Sep 24, 2016·American Journal of Preventive Medicine·Quinn H GrundyLisa A Bero
Oct 14, 2016·BMJ : British Medical Journal·Jonathan Ac SterneJulian Pt Higgins
Oct 19, 2016·Journal of Pediatric and Adolescent Gynecology·Jennifer E DietrichLakshmi V Srivaths
Oct 26, 2016·Epilepsia·Lia de Leon ErnstJacqueline A French
Nov 9, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Shaoyan FengHuabin Li
Apr 8, 2017·Stroke; a Journal of Cerebral Circulation·Daniel L LabovitzAdam Hanina

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