The Impact of Nocturia on Mortality: A Systematic Review and Meta-Analysis

The Journal of Urology
Jori S PesonenKari A O Tikkinen

Abstract

Nocturia (waking from sleep at night to void) is a common cause of sleep disruption associated with increased comorbidity and impaired quality of life. However, its impact on mortality remains unclear. We performed a systematic review and meta-analysis to evaluate the association of nocturia with mortality as a prognostic factor and a causal risk factor. We searched PubMed®, Scopus®, CINAHL® (Cumulative Index of Nursing and Allied Health Literature) and major conference abstracts up to December 31, 2018. Random effects meta-analyses were done to address the adjusted RR of mortality in people with nocturia. Meta-regression was performed to explore potential determinants of heterogeneity, including the risk of bias. We applied the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) framework to rate the quality of evidence for nocturia as a prognostic risk factor for mortality and separately as a cause of mortality. Of the 5,230 identified reports 11 observational studies proved eligible for inclusion. To assess nocturia 10 studies used symptom questionnaires and 1 used frequency-volume charts. Nocturia was defined as 2 or more episodes per night in 6 studies (55%) and as 3 or more episodes per night in 5 (45...Continue Reading

Citations

Nov 10, 2018·Prostate Cancer and Prostatic Diseases·Jonne ÅkerlaAnssi Auvinen
Jun 6, 2020·Neurourology and Urodynamics·Curran J EmeruwaJeffrey P Weiss
Sep 25, 2020·International Journal of Clinical Practice·Ozan BozkurtUNKNOWN Aegean Study Group of the Society of Urological Surgery
Oct 22, 2020·Neurourology and Urodynamics·Georgina BainesPhilip Toozs-Hobson
Nov 25, 2020·Drugs & Aging·Dylan T WolffJeffrey P Weiss
Dec 15, 2020·Brain Injury : [BI]·Stefania MuscoGianfranco Lamberti
Jan 14, 2021·International Urogynecology Journal·Kim PauwaertKarel Everaert
Jan 19, 2021·Journal of Exercise Rehabilitation·Gun Hyun ParkYoung Sam Cho
Jun 20, 2021·Neurourology and Urodynamics·Donald L Bliwise
Aug 17, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Makito MiyakeKiyohide Fujimoto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the Staff Meetings
P B FOWLER
Australian Family Physician
Robert McRitchie
JAMA : the Journal of the American Medical Association
M D Decker
Advances in Experimental Medicine and Biology
Jeffrey P Weiss, Jerry G Blaivas
© 2021 Meta ULC. All rights reserved