The impact of non-severe hypoglycemia on quality of life in patients with type 2 diabetes

Journal of Diabetes and Its Complications
William H PolonskyDanielle Hessler

Abstract

To determine the impact of frequency of non-severe hypoglycemic events (NSHE) and the perceived burden of NSHE on quality of life (QOL) over time. T2D adults (n = 424) were re-contacted two years after initial QOL assessment. Responding subjects (n = 290) reported the frequency and burden of NSHE over time and completed six generic and diabetes-specific QOL measures. Most subjects (86%) reported ≥ one NSHE over time. Higher frequency of NSHE was significantly associated with decrements in QOL. Greater perceived burden of NSHE was significantly linked to decreases in QOL over time for all six QOL measures. Interaction terms indicated that participants with a higher frequency of NSHE and higher perceived burden reported the greatest decrease in QOL; participants who experienced frequent NSHE but did not perceive these events as burdensome evidenced little worsening in QOL over time. NSHE have a negative impact on QOL over time in T2D adults. However, it is not just the occurrence of NSHE that affects QOL; it is the individual's felt burden of these events that is critical. The greatest reductions in QOL are seen among those subjects reporting a higher frequency of NSHE and indicating that such events are burdensome.

Citations

Sep 11, 2019·Diabetes Technology & Therapeutics·Suresh Rama ChandranDaphne S L Gardner
Mar 17, 2020·Expert Review of Endocrinology & Metabolism·Laure Sayyed Kassem, David C Aron
Dec 14, 2018·The Diabetes Educator·Davida F KrugerChristopher G Parkin
Jul 3, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Chioma UzoigweMichael S Radin
Oct 23, 2020·Journal of Clinical Nursing·Yu ZhangMark Hayter
Mar 29, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Manon CoolenFrans Pouwer
Apr 11, 2021·Journal of Diabetes and Its Complications·Lizheng ShiBelinda Childs
Oct 2, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Kevin A MatlockUNKNOWN Hypo-RESOLVE consortium

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