The impact of parental postpartum pertussis vaccination on infection in infants: A population-based study of cocooning in Western Australia

Vaccine
Dale CarcionePaul V Effler

Abstract

During a pertussis epidemic in 2011-2012 the Western Australian (WA) Department of Health implemented a 'cocooning' programme, offering free pertussis-containing vaccine (dTpa) to new parents. We assessed the impact of vaccinating parents with dTpa on the incidence of pertussis infection in newborns. Births in WA during 2011-2012 were linked to a register of parental pertussis vaccinations and to notified reports of laboratory-proven pertussis in children <6 months of age. Parents who received dTpa during the four weeks after their child's birth were defined as 'vaccinated postpartum.' Cox proportional-hazards methods were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of pertussis infection among infants born to parents vaccinated postpartum vs. unvaccinated parents, adjusted for maternal age, geographic region, timing of birth, and number of siblings. Of 64,364 live-births, 43,480 (68%) infants had at least one vaccinated parent (60% of mothers and 36% of fathers). After excluding records where parent(s) were either vaccinated prior to the birth, vaccinated >28 days after the birth, the vaccination date was uncertain, or the child died at birth (n=42), the final cohort contained 53,149 c...Continue Reading

References

Dec 4, 2003·Australian and New Zealand Journal of Public Health·Brynley P HullPeter B McIntyre
Jun 25, 2004·The Journal of Infectious Diseases·C Mary HealyCarol J Baker
Aug 7, 2004·Vaccine·Annelies Van Rie, Herbert W Hethcote
Jun 1, 2007·The Lancet Infectious Diseases·Frits R Mooi, Sabine C de Greeff
Jul 15, 2009·Academic Pediatrics·Emmanuel B WalterRowena J Dolor
Apr 8, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S C de GreeffH E de Melker
Jan 29, 2011·American Journal of Obstetrics and Gynecology·Stanley A GallMichael Pichichero
Sep 14, 2012·BMC Medical Research Methodology·Matthew N CooperElizabeth Milne
Nov 28, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jason M WarfelTod J Merkel
Jul 6, 2014·The Pediatric Infectious Disease Journal·C Mary HealyLuis A Castagnini
Jul 20, 2014·BMC Infectious Diseases·Pascal Urwyler, Ulrich Heininger

❮ Previous
Next ❯

Citations

Oct 8, 2016·Human Vaccines & Immunotherapeutics·Eleonora AgricolaAlberto E Tozzi
Nov 14, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Amy E BlainTami H Skoff
Feb 28, 2018·Expert Review of Vaccines·Federico Martinón-TorresCarl Heinz Wirsing von König
Oct 14, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tami H SkoffStacey W Martin
Dec 1, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Saskia van der LeeGuy A M Berbers
Sep 27, 2018·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Priya Darshene JanagarajRosalind Webby
Feb 24, 2019·BMJ : British Medical Journal·Dipesh P GopalDaniel Toeg
Oct 28, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Eleonora BrilloErsilia Buonomo
Oct 30, 2020·Expert Review of Vaccines·Say-Yed Hesameddin Tafreshi
Nov 12, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ariel M SlifkaMark K Slifka
Mar 6, 2021·Expert Review of Vaccines·Camille Locht
Mar 30, 2018·Science Translational Medicine·Matthieu Domenech de CellèsPejman Rohani
May 31, 2017·Pediatrics·Roger BaxterNicola P Klein

❮ Previous
Next ❯

Related Concepts