The Impact of Patent Expiry on Drug Prices: A Systematic Literature Review

Applied Health Economics and Health Policy
Gerard T VondelingMark H Rozenbaum

Abstract

The aim of this study was to evaluate the impact of patent expiry on drug prices by means of a systematic literature review. A systematic literature search was performed in PubMed to identify all published literature on the impact of patent expiration on drug prices. Additional literature was identified using a less distinct syntax in Google Scholar and EconLit. Data extraction followed a standardized assessment form containing the domains study type, study aim, reported outcomes, number of drugs and drug classes assessed, and originators or generics assessed. The 16 identified studies that assessed impact of patent expiry on drug prices showed that price developments after patent expiration varied between countries. The included studies assessed price developments for the USA, Canada, Australia, the UK, the Netherlands, Germany and France, Spain, Italy, Norway, Sweden and Denmark. The number of drugs included within different studies ranged between 1 and 219. The identified studies indicated that drug prices decreased significantly after patent expiry with drug price ratios ranging from 6.6 to 66% 1-5 years after patent expiry. Drug prices decrease significantly after patent expiry. The extent of this price reduction varied gr...Continue Reading

References

Sep 29, 2004·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Laura MagazziniMassimo Riccaboni
Nov 23, 2005·Journal of Managed Care Pharmacy : JMCP·Song Hee HongThomas T H Wan
Nov 29, 2005·Applied Health Economics and Health Policy·Cornelis BoersmaMaarten J Postma
May 9, 2007·Health Affairs·Ernst R BerndtEdward Tuttle
Jun 10, 2010·The Medical Journal of Australia·Philip M Clarke, Edmund M Fitzgerald
Aug 24, 2010·Journal of Managed Care Pharmacy : JMCP·Joshua N Liberman, M Christopher Roebuck
Aug 8, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Alexandra CameronRichard Ogilvie Laing
Oct 25, 2012·Southern Med Review·Sabine VoglerKees de Joncheere
Feb 2, 2013·International Journal of Pharmaceutical Investigation·Shweta HandooSusanta Kumar Sahu
Dec 11, 2013·Journal of Medical Economics·Henry GrabowskiRichard Mortimer
Feb 20, 2014·Applied Health Economics and Health Policy·Christina M L KeltonPamela C Heaton
Apr 12, 2016·Journal of Medical Economics·Henry GrabowskiAni Boyo

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Citations

Jul 13, 2019·Expert Opinion on Therapeutic Patents·Esteban Ortiz-PradoLenin Gómez-Barreno
Oct 30, 2018·Applied Health Economics and Health Policy·Carlos Vílchez-RománEdward Mezones-Holguín
Dec 15, 2020·Journal of Market Access & Health Policy·Simon van der SchansMark H Rozenbaum
Feb 26, 2021·TheScientificWorldJournal·José F Santos-NetoBruna A S Machado

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Software Mentioned

EconLit
Originator
Generic Originator
USA Originator
Generic
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