The impact of patient-perceived restricted access to anti-TNF therapy for rheumatoid arthritis: a qualitative study.

Musculoskeletal Care
Tessa SandersonS Hewlett

Abstract

To explore rheumatoid arthritis (RA) patients' experience of access to anti-tumour necrosis factor (anti-TNF) therapy in the UK, and of switching therapies after an initial failure. Patients were asked about their experience of accessing, receiving and discontinuing anti-TNF therapy in face-to-face indepth interviews, within the context of the larger study about treatment outcomes. Seventeen individuals with a diagnosis of RA and experience of receiving anti-TNF therapy were interviewed in one hospital trust in England. Different emotions (Theme 1) surrounded the process of accessing anti-TNF therapy: hope, desperation, apprehension, anxiety and frustration. Experience of receiving anti-TNF therapy (Theme 2) included not only positive transformation, but also fear of failure and discontinuation. The subsequent value that patients placed on anti-TNF therapy (Theme 3) included having a right to receive therapy and being lucky. These three themes were underpinned by the core category of 'willing to try anything'. Those switching therapies reported increased caution over the possibility of recurring side effects, but some suggestion of benefit. There was a perception that access to anti-TNF therapy was restricted by cost, rather th...Continue Reading

References

Oct 10, 1992·BMJ : British Medical Journal·A T Elder, K A Fox
Feb 1, 1980·Arthritis and Rheumatism·J F FriesH R Holman
Jul 30, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S J StraussJ S Whelan
Oct 30, 2003·The Cochrane Database of Systematic Reviews·B BlumenauerG Wells
Dec 4, 2003·Journal of Psychosomatic Research·Gerhard Strauss-BlascheWolfgang Marktl
Jan 15, 2004·Annals of the Rheumatic Diseases·F C BreedveldR N Maini
Jan 3, 2006·Joint, Bone, Spine : Revue Du Rhumatisme·Marcia S GentaCem Gabay
Mar 2, 2006·Arthritis Research & Therapy·Juan J Gomez-ReinoUNKNOWN BIOBADASER Group
Aug 26, 2006·Nature Clinical Practice. Rheumatology·Maya H Buch, Paul Emery
Oct 17, 2006·Rheumatology·L J KayUNKNOWN BSR Biologics Register Management committee
Oct 17, 2006·Musculoskeletal Care·Jill Edwards
Oct 17, 2006·Musculoskeletal Care·Sarah HewlettRod Hughes
Nov 1, 2006·Nature Clinical Practice. Rheumatology·Edward C Keystone
Aug 30, 2007·Musculoskeletal Care·Frances Chilton, Raymond A Collett
Oct 9, 2007·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Magdalena DziadzioClare Higgens

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Citations

Jul 10, 2010·International Journal of Qualitative Studies on Health and Well-being·Ingrid LarssonBarbro Arvidsson
Jan 1, 2014·Rheumatology International·Fatma Ilknur CinarSalih Pay
Apr 17, 2012·Arthritis Care & Research·Heather F BurnettWendy J Ungar
Jan 19, 2020·The British Journal of Dermatology·B TrettinH Agerskov
Jun 2, 2017·Modern Rheumatology·Louise T BendahanMarcelo M Pinheiro
Jan 19, 2019·Advances in Rheumatology·Penélope Esther PalominosLaure Gossec

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