The Impact of Renal Impairment on Short-term Morbidity Risk Following Lumbar Spine Surgeries

Spine
Christopher T MartinStuart L Weinstein

Abstract

Retrospective review of prospectively collected data. To determine a cutoff below which worsening renal function is associated with increased risk of morbidity and to determine the types and magnitude of morbidity associated with renal impairment. Renal impairment is associated with an increased risk of morbidity after lumbar spine surgery. However, the degree to which increasing levels of renal dysfunction are associated with morbidity has not been well defined. A large, multicenter, clinical registry was queried for all adult patients undergoing lumbar spine surgery in 2012, and 13,576 cases were identified. An estimated glomerular filtration rate (eGFR) was calculated for each patient. Propensity scores were used to match patients on the basis of preoperative comorbidities and the procedure-type performed. The incidence of 30-day morbidity was then compared between patients with no or mild renal impairment (eGFR ≥60 mL/min/1.73 m) and those with moderate or severe disease (eGFR <60 mL/min/1.73 m). Separately, the morbidity risk associated with eGFR was analyzed as a continuous variable. The risk of morbidity increased with worsening eGFR in an inverse-logarithmic fashion (R = 0.84), and the magnitude of risk increased substa...Continue Reading

References

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Citations

Dec 26, 2015·The Spine Journal : Official Journal of the North American Spine Society·Michael P SilversteinThomas E Mroz
Dec 15, 2017·Global Spine Journal·Rachel S BronheimSamuel K Cho

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