Abstract
Antifreeze (glyco)proteins (AF(G)Ps) have received increasing attention as potential cryopreservation agents since their discovery in the 1970s. While cryopreservation strategies for specific cells (such as red blood cells) are successful and widely implemented, preservation of other cell types, tissues and whole organs remains challenging. This is due to the multifactorial nature of the freeze-thaw damage, the complexity of preserving biological matter and the (country-to-country) variability of the employed procedures and regulations. AF(G)Ps are well-known for their ability to modulate ice crystal growth morphology and ice recrystallization inhibition (IRI), both of which are considered key contributors to freeze-thaw damage. To date, however, the impact of AF(G)Ps on cell survival remains at best partially understood as conflicting results on the benefits or disadvantages of including AF(G)P in cryopreservation strategies remain unelucidated. We hypothesize that variability in the additives in the cryopreservation media contributes to the observed discrepancies. To critically examine this idea, we monitored the inhibition of ice recrystallization by AF(G)P in the presence of various salts using a quantitative analysis of op...Continue Reading
References
Oct 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·J F Carpenter, T N Hansen
Jun 11, 1971·Science·A L DeVries
Sep 1, 1984·The American Journal of Physiology·P Mazur
Apr 1, 1994·Cryobiology·T WangA L Devries
Oct 6, 2000·Cryobiology·J H Wang
Mar 28, 2002·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·J G Duman
Apr 27, 2005·Transfusion Medicine Reviews·Kirby L ScottJason P Acker
Oct 13, 2006·Current Opinion in Chemical Biology·Yanjie Zhang, Paul S Cremer
Jul 16, 2008·Biochimica Et Biophysica Acta·Natapol AmornwittawatXin Wen
Aug 16, 2008·Cryobiology·Erlend KristiansenKarl Erik Zachariassen
May 5, 2009·Journal of Biotechnology·Zhen Yang
Aug 27, 2009·The Journal of Physical Chemistry. B·C BudkeT Koop
Sep 26, 2009·The Journal of Physical Chemistry. B·Sen WangXin Wen
Jan 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Konrad MeisterMartina Havenith
Aug 8, 2014·Chemical Society Reviews·Andrea Salis, Barry W Ninham
May 6, 2015·PloS One·Jaewang LeeSeok Hyun Kim
Jan 21, 2016·Biointerphases·Anneloes S Oude VrielinkIlja K Voets
Mar 5, 2016·Proceedings of the National Academy of Sciences of the United States of America·Luuk L C OlijveIlja K Voets
Jan 31, 2017·Marine Drugs·Hak Jun KimBon-Won Koo
Apr 22, 2017·Cryobiology·Gloria D ElliottBarry J Fuller
Jul 22, 2018·Journal of the American Chemical Society·Konrad MeisterRan Drori
Citations
Oct 20, 2019·International Journal of Molecular Sciences·Romà Surís-Valls, Ilja K Voets
Apr 9, 2020·The Analyst·Alice FayterMatthew I Gibson
Oct 23, 2020·Extremophiles : Life Under Extreme Conditions·Elizabeth A DeleskyWil V Srubar
Feb 3, 2021·Cryobiology·Audrey K GrunebergPeter L Davies
Mar 12, 2020·International Journal of Biological Macromolecules·Hong XiangYong Hu
Mar 12, 2021·Materials Horizons·Panagiotis G GeorgiouMatthew I Gibson
May 5, 2021·Biomacromolecules·Zhang LiuJianjun Wang
Jul 6, 2021·RSC Medicinal Chemistry·Trisha L BaileyMatthew I Gibson
Dec 1, 2021·Biomacromolecules·Huba L MartonMatthew I Gibson