The impact of septodermoplasty and potassium-titanyl-phosphate (KTP) laser therapy in the treatment of hereditary hemorrhagic telangiectasia-related epistaxis

American Journal of Rhinology
Richard J HarveyValerie J Lund

Abstract

A variety of modalities are available for the control of recurrent epistaxis in hereditary hemorrhagic telangiectasia (HHT). Laser ablation, in particular potassium-titanyl-phosphate (KTP), has gained popularity as it coagulates the telangiectasia with minimal peripheral tissue injury. Septodermoplasty (SDP) also can be performed in the day surgery setting. Telangiectasia recurred, necessitating repeated treatments. The frequency and interval between procedures is not well documented. The purpose of this study was to describe the frequency of surgical interventions for HHT patients and the impact of SDP. A retrospective review was undertaken of procedures performed in a tertiary hospital unit during a 60-month period for HHT. The incidence of KTP laser and SDP, days between treatments, total number of interventions and perioperative hemoglobin (Hb) were audited. Patient groups were identified as definite or possible HHT according to the Curaçao criteria. All suffered from epistaxis sufficient to seek medical treatment. Three hundred one procedures were performed on 131 patients during the study period. In total, 33 SDPs and 268 KTP laser treatments were performed; 78.3% of patients required three or less procedures. The mean ti...Continue Reading

References

Nov 1, 1977·Archives of Otolaryngology·T V McCaffreyC F Lake
Sep 1, 1992·Archives of Otolaryngology--head & Neck Surgery·G P Bridger
Nov 11, 1991·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·M B SiegelM R Rosen
Sep 11, 1991·The Laryngoscope·O S AAssarR I White
Jan 1, 1989·The Annals of Otology, Rhinology, and Laryngology·H L Levine
Mar 1, 1983·The Journal of Laryngology and Otology·C UlsøP Stoksted
Aug 1, 1995·Annals of Plastic Surgery·E E RebeizS M Shapshay
Sep 1, 1994·The Journal of Laryngology and Otology·A A Hosni, A J Innes
Jul 1, 1994·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·L EldenD Charles
Jan 1, 1997·American Journal of Rhinology·S V ByahattiS M Shapshay
Feb 24, 1998·The Journal of Laryngology and Otology·P G HarriesJ A Carruth
Sep 15, 1999·American Journal of Rhinology·V J Lund, D J Howard
Apr 6, 2000·American Journal of Medical Genetics·C L ShovlinH Plauchu
Aug 2, 2002·The Laryngoscope·Rahul K ShahStanley M Shapshay
Sep 6, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Haneen SadickWolfgang Bergler
Jul 18, 1957·The New England Journal of Medicine·R M BIRDR R ROBINSON
Feb 4, 2005·The Laryngoscope·Maria Luisa FiorellaRobert I White
Dec 13, 2005·QJM : Monthly Journal of the Association of Physicians·M GallitelliC Sabbà
May 19, 2006·Auris, Nasus, Larynx·Keiichi IchimuraKen-ichi Nakamura

❮ Previous
Next ❯

Citations

Aug 2, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·C RohrmeierT S Kuehnel
Jan 16, 2013·Journal of the American Academy of Dermatology·Breck ThrashAlan Menter
Jan 13, 2016·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Christopher J ChinIan J Witterick
Jan 12, 2016·International Forum of Allergy & Rhinology·Benjamin H TimminsP Daniel Ward
Dec 31, 2015·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Mark Bastianelli, Shaun J Kilty
Jul 25, 2015·British Journal of Haematology·Urban W GeisthoffUlrich Seyfert
Jan 31, 2012·International Forum of Allergy & Rhinology·Holly BoyerGeorge Goding
Nov 21, 2012·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·P M SpielmannP S White
Feb 14, 2013·The Laryngoscope·B Maneesha SilvaClaire L Shovlin
May 9, 2012·International Forum of Allergy & Rhinology·Nathan B Sautter, Timothy L Smith
Jun 5, 2013·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·M P EllisR Almeyda
May 2, 2014·International Forum of Allergy & Rhinology·Douglas D RehChristian A Merlo
Mar 5, 2015·The Journal of Laryngology and Otology·I Syed, V S Sunkaraneni
Jun 9, 2016·Otolaryngologic Clinics of North America·Nathan B Sautter, Timothy L Smith
Jul 6, 2016·The Journal of Laryngology and Otology·S Jervis, D Skinner
Feb 23, 2018·The Laryngoscope·Johan SteinegerSinan Dheyauldeen
Apr 22, 2009·American Journal of Rhinology & Allergy·Fabio PagellaCesare Danesino
Jun 5, 2013·American Journal of Rhinology & Allergy·Raymond SacksRakesh Chandra
Nov 22, 2012·American Journal of Rhinology & Allergy·Sara L RicherDouglas A Ross
Aug 9, 2011·American Journal of Rhinology & Allergy·Sinan DheyauldeenGregor Bachmann-Harildstad
Jul 9, 2013·The Laryngoscope·Joanne Rimmer, Valerie J Lund
May 21, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Hanny Al-SamkariVivek N Iyer
Dec 18, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jonas Hjelm Andersen, Anette Drøhse Kjeldsen
Apr 13, 2013·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·J Rimmer, V J Lund
Jul 15, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jane Y TongRobert T Sataloff
Mar 16, 2017·International Forum of Allergy & Rhinology·Thomas ParzefallDominik Riss
May 1, 2013·American Journal of Rhinology & Allergy·Raymond SacksRakesh Chandra
Jul 25, 2020·Ear, Nose, & Throat Journal·Kimberley LauJaydip Ray
Aug 24, 2019·Lasers in Surgery and Medicine·Arash AbiriEdward C Kuan
Nov 15, 2016·Current Opinion in Otolaryngology & Head and Neck Surgery·Michael D Lupa, Sarah K Wise
Nov 4, 2020·BMJ Case Reports·Eve Mandisa Rader Bowers, Stella Lee
Mar 5, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Cilgia DürM Caversaccio
Mar 23, 2021·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Fabio PagellaElina Matti

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