The impact of the scale-up of malaria rapid diagnostic tests on the routine clinical diagnosis procedures for febrile illness: a series of repeated cross-sectional studies in Papua New Guinea

Malaria Journal
Justin PulfordManuel W Hetzel

Abstract

This paper examines the impact of the scale-up of malaria rapid diagnostic tests (RDT) on routine clinical diagnosis procedures for febrile illness in primary healthcare settings in Papua New Guinea. Repeat, cross-sectional surveys in randomly selected primary healthcare services were conducted. Surveys included passive observation of consecutive febrile case management cases and were completed immediately prior to RDT scale-up (2011) and at 12- (2012) and 60-months (2016) post scale-up. The frequency with which specified diagnostic questions and procedures were observed to occur, with corresponding 95% CIs, was calculated for febrile patients prescribed anti-malarials pre- and post-RDT scale-up and between febrile patients who tested either negative or positive for malaria infection by RDT (post scale-up only). A total of 1809 observations from 120 health facilities were completed across the three survey periods of which 915 (51%) were prescribed an anti-malarial. The mean number of diagnostic questions and procedures asked or performed, leading to anti-malarial prescription, remained consistent pre- and post-RDT scale-up (range 7.4-7.7). However, alterations in diagnostic content were evident with the RDT replacing body tempe...Continue Reading

References

Jun 12, 2003·Trends in Parasitology·Ivo MüllerTom Smith
Nov 23, 2010·Tropical Medicine & International Health : TM & IH·Frank BaidenDaniel Chandramohan
Dec 27, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nicolas SennBlaise Genton
Mar 13, 2012·Health Policy and Planning·Tamara Hafner, Jeremy Shiffman
Feb 19, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F ChappuisC P Yansouni
Nov 18, 2017·Bulletin of the World Health Organization·Manuel W HetzelIvo Mueller

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