The impact of vaccination on influenza-related respiratory failure and mortality in hospitalized elderly patients over the 2013-2014 season

The Open Respiratory Medicine Journal
Manish JoshiThaddeus Bartter

Abstract

Seasonal Influenza ("the flu") is a respiratory illness caused by influenza viruses. Yearly influenza vaccination is considered to be protective against illness and/or severity of illness and is recommended by CDC for all individuals > 6 months of age. However, the effectiveness of influenza vaccine in older individuals has come under question. To describe the clinical characteristics and treatment outcomes of patients admitted to an academic tertiary care Veterans Administration hospital with influenza during the 2013-2014 influenza season and determine the impact, if any, of prior influenza vaccination upon patient outcomes. Medical electronic records were searched for all patients admitted to the Little Rock Veterans Administration Hospital with proven influenza during the 2013-2014 influenza season. Cohorts of vaccinated and non-vaccinated patients were then compared to determine the impact of prior influenza vaccination upon respiratory-failure and mortality. Seventy patients met selection criteria. Mean age was 66 years. Sixty-four (91%) patients had at least one underlying co-morbid condition; these conditions included COPD, congestive heart failure, diabetes, and cancer. 60/70 (85%) tested positive for Influenza A, and ...Continue Reading

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Citations

Dec 8, 2015·Archives of Medical Research·José Luis Sandoval Gutierrez, Edgar Sevilla Reyes
May 20, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Carmen ArriolaSandra S Chaves
Jan 7, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Monica L NationAllen C Cheng
Oct 29, 2020·Toxicology Reports·Ronald N KostoffAristidis Tsatsakis
Mar 9, 2021·Journal of Burn Care & Research : Official Publication of the American Burn Association·Kirsty NwezeKayvan Shokrollahi
Jun 28, 2021·Medicina intensiva·N J ProañosUNKNOWN on behalf GETGAG SEMICYUC Working Group

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BETA
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SAS

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