The impact of ventilation tubes in otitis media on the risk of cholesteatoma on a national level

International Journal of Pediatric Otorhinolaryngology
Bjarki Ditlev DjurhuusChristian Emil Faber

Abstract

To estimate the impact of treatment with middle ear ventilation tube insertion (VTI) in children with otitis media (OM) on the risk of cholesteatoma on a national level. Data were obtained from the Danish National Patient Register, the National Health Service Register and Statistics Denmark. Cumulative incidence proportions were estimated by the Kaplan-Meier method and hazard ratios with Cox regression analysis. The first surgically treated middle ear cholesteatoma in a child (STMEC1) was considered an event. A total of 217,206 children, born after December 31, 1996, who had VTI from January 1, 1997 to August 31, 2011 were identified. Of these, 374 subsequently had a STMEC1. A corresponding 36,981 children without any VTI were identified for comparison using a random 5% sample of the Danish population. Of these, 5 had a STMEC1. The cumulative incidence proportion with STMEC1 at 12 years of age for children with 0, 1, 2, 3, and ≥4 VTI's was 0.04% (95% confidence interval 0.02-0.12%), 0.21% (0.18-0.26%), 0.35% (0.28-0.43%), 0.40% (0.30-0.54%), and 0.55% (0.44-0.70%), respectively. In the regression model each additional year of age before the first VTI increased the risk of STMEC1 by 54% (47-63%), while each additional year betwe...Continue Reading

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Jul 27, 2014·International Journal of Pediatric Otorhinolaryngology·Bjarki Ditlev DjurhuusChristian Emil Faber
Dec 17, 2014·International Journal of Pediatric Otorhinolaryngology·Bjarki Ditlev DjurhuusChristian Emil Faber

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Citations

Feb 10, 2016·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Ville LehtonenVuokko Anttonen
Feb 23, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Jason A BeyeaStephen F Hall
Mar 15, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Jason A BeyeaStephen F Hall
Jun 1, 2017·Pediatrics·Dale W SteeleThomas A Trikalinos

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