The Impella Microaxial Flow Catheter Is Safe and Effective for Treatment of Myocarditis Complicated by Cardiogenic Shock: An Analysis From the Global cVAD Registry

Journal of Cardiac Failure
Shiva K AnnamalaiNavin K Kapur

Abstract

Myocarditis complicated by cardiogenic shock remains a complex problem. The use of acute mechanical circulatory support devices for cardiogenic shock is growing. We explored the utility of Impella transvalvular microaxial flow catheters in the setting of myocarditis with cardiogenic shock. We retrospectively analyzed data from 21 sites within the cVAD registry, an ongoing multicenter voluntary registry at sites in North America and Europe that have used Impella in patients with myocarditis. Myocarditis was defined by endomyocardial biopsy (n = 11) or by clinical history without angiographic evidence of coronary disease (n = 23). A total of 34 patients received an Impella 2.5, CP, 5.0, or RP device for cardiogenic shock complicating myocarditis. Baseline characteristics included age 42 ± 17 years, left ventricular ejection fraction (LVEF) 18% ± 10%, cardiac index 1.82 ± 0.46 L·min-1·m-2, pulmonary capillary wedge pressure 25 ± 7 mm Hg, and lactate 27 ± 31 mg/dL. Before Impella placement, 32% (n = 11) of patients required intra-aortic balloon pump. Mean duration of Impella support was 91 ± 74 hours; 21 of 34 patients (62%) survived the index hospitalization and were discharged with an improved mean LVEF of 37.32% ± 20.31% (P = .0...Continue Reading

Citations

Jun 17, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Danny RamzyMark Anderson
Mar 23, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Bernhard WernlyAlexander Lauten
Dec 8, 2019·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·D I M van DortG S C Geuzebroek
Oct 14, 2020·Nature Reviews. Cardiology·Carsten TschöpeSophie Van Linthout
Nov 13, 2020·Circulation. Heart Failure·Enrico AmmiratiPaolo G Camici
Jun 27, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Naoki TadokoroTomoyuki Fujita

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.

Related Papers

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
W P DembitskyC E Moreno-Cabral
Journal of the American Heart Association
Sudeep KuchibhotlaNavin K Kapur
© 2022 Meta ULC. All rights reserved