The importance of anxiety in both major depression and bipolar disorder

Depression and Anxiety
D P Goldberg, Jan Fawcett

Abstract

Generalized anxiety disorder (GAD) is frequently co-morbid with major depression (MDD), and this becomes more so when the duration requirement is relaxed. Both anxiety diagnoses and anxious symptoms are more common in both unipolar and bipolar depression. This paper explores the relationship between anxious symptoms and GAD with both unipolar and bipolar depression. MDD and bipolar disorder (BPD) are compared in three important respects: the extent of their co-morbidity with anxious symptoms and GAD, the effects that anxiety has on outcome of MDD and BPD, and the effects that anxiety has on the probability of suicide in each disorder. Anxious diagnoses occur frequently in association with depressive disorders, albeit to a different extent in the various subtypes of depression. In both disorders, anxiety affects the outcome and makes suicidal thoughts, and completed suicide more likely. Anxious phenomena should be assessed whenever a depressive disorder is diagnosed. It is likely that the raised expectancy of anxious phenomena is related to an individual's premorbid level of negative affect, and it is possible that suicidal phenomena are related to subthreshold hypomanic symptoms.

References

Jan 1, 1992·The American Journal of Psychiatry·W CoryellG Winokur
Nov 1, 1991·The American Journal of Psychiatry·P J ClaytonJ Fawcett
Sep 1, 1990·The American Journal of Psychiatry·J FawcettR Gibbons
May 17, 1995·Journal of Affective Disorders·M B SteinM Terepa
Jan 1, 1994·European Archives of Psychiatry and Clinical Neuroscience·T Bronisch, H U Wittchen
Sep 1, 1994·Journal of General Internal Medicine·P Roy-ByrneM Liebowitz
Oct 26, 1999·Archives of General Psychiatry·R F Krueger
Jun 1, 2000·The American Journal of Psychiatry·U FeskeD J Kupfer
Jun 29, 2001·Archives of General Psychiatry·W A VolleberghJ Ormel
Feb 5, 2002·European Archives of Psychiatry and Clinical Neuroscience·P TyrerT Johnson
Sep 10, 2003·Archives of General Psychiatry·Dean F MacKinnonJ Raymond DePaulo
Jul 2, 2004·The American Journal of Psychiatry·Giovanni B CassanoDavid J Kupfer
Jun 9, 2005·Archives of General Psychiatry·Ronald C KesslerEllen E Walters
Jul 16, 2005·Archives of Suicide Research : Official Journal of the International Academy for Suicide Research·Jules AngstAlex Gamma
Sep 30, 2005·Journal of Child and Adolescent Psychopharmacology·Daniel P DicksteinEllen Leibenluft
Dec 15, 2005·Journal of Abnormal Psychology·David Watson
Sep 6, 2006·Archives of General Psychiatry·Debra L FoleyAdrian Angold
Aug 8, 2007·Bipolar Disorders·Gregory E SimonJames Savarino
Jan 4, 2008·The American Journal of Psychiatry·Maurizio FavaMadhukar H Trivedi
May 21, 2008·Journal of Abnormal Psychology·Jennifer L TackettScott R Sponheim
Jun 23, 2009·Depression and Anxiety·Paul N PfeifferMarcia Valenstein
Aug 4, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Arnstein MykletunRobert Stewart
Oct 3, 2009·Psychological Medicine·D P GoldbergM J Hobbs
Oct 3, 2009·The American Journal of Psychiatry·William CoryellLewis L Judd
Dec 10, 2009·Archives of General Psychiatry·Petra ZimmermannJules Angst
Mar 13, 2010·Journal of Affective Disorders·Ayal SchafferAnthony Levitt
Nov 17, 2010·The American Journal of Psychiatry·Jess G FiedorowiczWilliam H Coryell
Aug 6, 2011·European Archives of Psychiatry and Clinical Neuroscience·J AngstA H Young

❮ Previous
Next ❯

Citations

May 16, 2013·BMC Medicine·Ian B HickiePatrick D McGorry
May 7, 2014·Der Nervenarzt·E Severus, M Bauer
Aug 30, 2014·Journal of Psychiatric Research·Elizabeth D BallardCarlos A Zarate
Dec 3, 2014·Asian Journal of Psychiatry·Valsamma Eapen, Rudi Črnčec
Dec 3, 2014·Clinical Psychology Review·Hannah J StratfordEmily A Holmes
Nov 26, 2015·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Li-Min XinTian-Mei Si
Aug 2, 2014·Scientific Reports·Claudia D van BorkuloLourens J Waldorp
Mar 28, 2013·Human Psychopharmacology·Dan J SteinSidney H Kennedy
Nov 28, 2013·Depression and Anxiety·David P Goldberg
Apr 24, 2016·Psychiatry Research·Jenelle Slavin-MulfordJennifer Zodan
Mar 3, 2015·Bipolar Disorders·Sanna PallaskorpiErkki Isometsä
Aug 3, 2014·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Katherine SanchezMadhukar H Trivedi
Aug 8, 2015·Wiener medizinische Wochenschrift·Wolfgang SpiegelPaul Fellinger
Jan 27, 2015·Current Psychiatry Reports·Fernando S Goes
Dec 21, 2016·International Journal of Psychiatry in Clinical Practice·Andrea AgugliaGiuseppe Maina
Nov 8, 2013·The Australian and New Zealand Journal of Psychiatry·David Goldberg
Nov 2, 2016·The Cochrane Database of Systematic Reviews·Ilaria GaliziaAllan H Young
Mar 13, 2014·Depression and Anxiety·Gustavo H VázquezLeonardo Tondo
Aug 5, 2018·Acta Psychiatrica Scandinavica·C HanssonM Landén
Sep 7, 2018·Perspectives in Psychiatric Care·Silvia D SerafimMaurício Kunz
Mar 2, 2019·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Sir David Goldberg
May 18, 2019·Expert Review of Neurotherapeutics·Mbemba Jabbi, Charles B Nemeroff
Jun 30, 2019·Evidence-based Mental Health·Gin MalhiTim Outhred
Oct 2, 2014·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Shaofang XuWei Wang
Jul 10, 2019·The International Journal of Neuropsychopharmacology·Chun-Jen HuangWei-Cheng Yang
Aug 31, 2020·International Journal of Methods in Psychiatric Research·Michael O KillianMadhukar H Trivedi
May 28, 2015·Annals of the New York Academy of Sciences·Jack D Barchas, Benjamin D Brody
Oct 13, 2017·Nordic Journal of Psychiatry·Gianluca SerafiniMario Amore
Mar 23, 2019·Behavioral Sciences & the Law·Allison SchuckIgor Galynker
Aug 29, 2019·Journal of Neural Transmission·Isabelle HäberlingGregor Berger
Apr 13, 2018·International Journal of Environmental Research and Public Health·Elżbieta GrochansAnna Jurczak
Nov 10, 2017·Current Opinion in Psychiatry·Roxanne GasperszBrenda W J H Penninx

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.