PMID: 8946456Nov 1, 1996Paper

The importance of different atrioventricular delay for left ventricular filling in sequential pacing: clinical implications

Pacing and Clinical Electrophysiology : PACE
M G ModenaG Mattioli

Abstract

We assessed the influence and clinical consequences of different AV delay on ventricular filling in 30 patients (mean age 60 +/- 5 years) who had DDD pacemakers for AV block. All 30 patients presented a normal ejection fraction, but in 18 cases (Group I), an echo-Doppler examination revealed ventricular hypertrophy (mean end-diastolic wall thickness of 1.4 +/- 0.16 cm, LV mass index 155 +/- 17 g/m2), and an abnormal relaxation pattern (isovolumetric relaxation time = 124.72 +/- 11.82; early to late peak velocity = 0.6 +/- 0.03; deceleration time = 296.83 +/- 34.02 ms). Group II included the remaining 12 patients who had a normal filling pattern. In all 30 patients, the pattern was reassessed following modification of the AV delay (200, 150, 100, and 75 ms). Patients at baseline (AV delay of 200 ms) also underwent an exercise test with determination of respiratory gas exchange. In Group I, 13 (72.5%) patients were classified as Weber class B (VO2 Max 16.8 +/- 1.7 mL/min per kg); and 5 (27.5%) were Class A (VO2 Max 22.5 +/- 1.4 mL/min per kg). In Group II, all 12 patients were classified as Weber Class A. In Group II, changes in AV delay caused no consistent variations in filling pattern, and therefore AV delay was not modified. ...Continue Reading

References

Mar 1, 1975·Archives of Internal Medicine·W J MandelK Obayashi
Jan 1, 1991·Annual Review of Medicine·B H Lorell
Mar 1, 1990·Journal of the American College of Cardiology·J B BedottoE J Eichhorn
Jul 15, 1990·The American Journal of Cardiology·M HochleitnerW Zechmann
Jan 1, 1987·Pacing and Clinical Electrophysiology : PACE·A WirtzfeldK Stangl
Jul 1, 1989·European Heart Journal·P RitterJ Gouffault
Oct 1, 1989·Journal of the American College of Cardiology·R A PhillipsL R Krakoff
May 1, 1987·Journal of the American College of Cardiology·B H Lorell, W Grossman
Oct 1, 1987·Journal of the American College of Cardiology·C Y ChoongM A Fifer
Sep 1, 1987·Journal of the American College of Cardiology·Z SassonR L Popp
Sep 1, 1987·Journal of the American College of Cardiology·M R ZileW H Gaasch
Sep 1, 1987·The American Journal of Cardiology·M WishA I Cohen
Nov 1, 1974·Circulation Research·W GrossmanM A Stefadouros
Aug 1, 1973·Journal of Applied Physiology·K WassermanW L Beaver
Mar 1, 1971·Clinical Pharmacology and Therapeutics·P Dauchot, J S Gravenstein
May 1, 1984·Pacing and Clinical Electrophysiology : PACE·V ParsonnetJ Maloney
Oct 1, 1980·The American Journal of Medicine·W Grossman
Dec 1, 1964·The American Journal of Cardiology·K WASSERMAN, M B MCILROY

❮ Previous
Next ❯

Citations

Feb 11, 1999·Journal of the American College of Cardiology·B SchwaabH Schieffer
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Frits L MeijlerJan Strackee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.