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The importance of study design for detecting differentially abundant features in high-throughput experiments

bioRxiv

Aug 14, 2014

Huaien LuoNiranjan Nagarajan

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Abstract

The use of high-throughput experiments, such as RNA-seq, to simultaneously identify differentially abundant entities across conditions has become widespread, but the systematic planning of such studies is currently hampered by the lack of general-purpose tools to do so. Here we demonstr...read more

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Biological Markers
Case-Control Studies
Research Design
EDDA
Statistical Test
Research Study
Nucleic Acid Sequencing
Gene Feature
Sequencing
Normalize
6
1
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  • The importance of study design for detecting differentially abundant features in high-throughput experiments

    bioRxiv

    Aug 14, 2014

    Huaien LuoNiranjan Nagarajan

    PMID: 990007948

    DOI: 10.1101/007948

    Abstract

    The use of high-throughput experiments, such as RNA-seq, to simultaneously identify differentially abundant entities across conditions has become widespread, but the systematic planning of such studies is currently hampered by the lack of general-purpose tools to do so. Here we demonstr...read more

    Mentioned in this Paper

    Biological Markers
    Case-Control Studies
    Research Design
    EDDA
    Statistical Test
    6
    1

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