PMID: 3752166Oct 1, 1986Paper

The importance of the abdominal viscera to peritoneal transport during peritoneal dialysis in the dog

The American Journal of the Medical Sciences
J RubinJ D Bower

Abstract

The authors sought to evaluate the dialyzing surfaces important for peritoneal dialysis. They reasoned that the most definitive way to evaluate whether any of the gut and associated membranes contributed to transport was to see if transport changed when they were removed. Paired studies measuring rates of peritoneal uptake of glucose, urea, and inulin were carried out in dogs. In the morning, the animals were tested with all peritoneal membranes intact. In the afternoon, the studies were repeated after evisceration. The mass transfer coefficients (MTC ml/min)--glucose (viscera 4.4 +/- 0.7, no viscera 4.9 +/- 0.3)--urea (viscera 16.8 +/- 2.4, no viscera 13.8 +/- 1.0);--inulin (viscera 1.6 +/- 0.6, no viscera 2.2 +/- 0.7) were not changed nor was the amount of mass absorbed significantly different. MTC and peritoneal absorption were unaffected by omentectomy, mesenterectomy, or evisceration. Whether these results were due to nonparticipation of these structures in peritoneal transport or other mechanisms await further studies.

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Citations

Apr 1, 1993·Diabetes/metabolism Reviews·S A Amiel
Apr 2, 1997·Journal of the National Cancer Institute·R L Dedrick, M F Flessner
Dec 1, 1989·The American Journal of the Medical Sciences·J RubinM Andrew
May 1, 1988·The American Journal of the Medical Sciences·J RubinQ Jones
May 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J Rubin, Q Jones
Jul 1, 1996·Kidney International·E R ZakariaB Rippe
Jul 1, 1990·Kidney International·J L BellL W Henderson
Sep 4, 2014·PloS One·Paulina M KowalewskaAlison E Fox-Robichaud
Oct 18, 2015·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Paulina M KowalewskaAlison E Fox-Robichaud
Sep 20, 2002·Journal of the American Society of Nephrology : JASN·Avry ChagnacUzi Gafter
May 23, 2003·Journal of the American Society of Nephrology : JASN·Bert-Inge Rosengren, Bengt Rippe

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