PMID: 2497756Apr 1, 1989Paper

The in vitro activity of norfloxacin, ofloxacin and ciprofloxacin and other antibiotics in current use against Neisseria gonorrhoeae

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
K Melby, A Faegri

Abstract

One hundred non-beta-lactamase-producing and 50 beta-lactamase-producing strains of Neisseria gonorrhoeae serogroup WI and WII/III were tested in vitro by an agar dilution method against a panel of antibiotics including ciprofloxacin, ofloxacin and norfloxacin. All strains irrespective of beta-lactamase production and serogroup allocation, were inhibited by 0.125 mg/l of all quinolones. Ciprofloxacin turned out to be most active followed by ofloxacin and norfloxacin. All strains were also inhibited by low concentrations of cefotaxime (MIC less than 0.25 mg/l). Many strains mostly among the beta-lactamase-producing strains were resistant (MIC greater than 4 mg/l) to doxycycline. Ampicillin is still active against the majority of non-beta-lactamase-producing strains. The majority of the strains belonged to serogroup WII/III which are known to be less sensitive to penicillin G and ampicillin.

Citations

Feb 1, 1991·Journal of Clinical Pathology·A TurnerK R Gough
Jul 21, 2005·Molecular Ecology·L ParducciK D Bennett
Aug 11, 2011·Anais Da Academia Brasileira De Ciências·Adriana M C HorbeRussell Mapes
May 9, 2012·Environmental Science and Pollution Research International·C HuguetM Sturm
Sep 5, 2012·The New Phytologist·Surangi W PunyasenaPietra G Mueller
Oct 3, 2012·Conservation Biology : the Journal of the Society for Conservation Biology·Jamie R WoodAlan Cooper
Aug 16, 2018·Royal Society Open Science·Matthew J WoollerJohn W Williams
Sep 10, 2014·Applications in Plant Sciences·Jing Ginger HanChi-Ren Shyu
Jan 28, 2015·Proceedings of the National Academy of Sciences of the United States of America·Tripti BhattacharyaSusan Zimmerman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.