PMID: 11317538Apr 25, 2001Paper

The in-vitro effect of constant and pulsating magnetic field on immunocompetent blood cells of hematologic patients

Voprosy onkologii
S S Bessmel'tsevT S Lavrushina

Abstract

Immunologic characteristics were studied in 103 patients with multiple myeloma, acute leukemia, chronic lymphocytic leukemia and non-Hodgkin's disease following in vitro exposure of blood to a low-intensity static field (SF) and alternating field (AF) or pulsating magnetic field (PF). In a SF-AF study of multiple myeloma, a 30 min exposure had a positive effect on expression of tumor cells and T-cell markers and stimulated the regulatory function of T-lymphocytes. With SF-AF and PF application alternating, the expression of both +CD3 and +CD4 and the +CD3/+CD4 ratio increased suggesting the lowering of immunological deficiency. In acute leukemia, a combined application of the magnetic fields had an effect on the helper activity of the T-lymphocyte subpopulation. The phagocytic activity of leukocytes increased significantly while their digestive ability rose to a moderate degree.

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