PMID: 15365924Sep 15, 2004Paper

The incidence and risk of acute renal failure after cardiac surgery

Journal of Cardiothoracic and Vascular Anesthesia
Tiziana BoveAlberto Zangrillo

Abstract

To evaluate outcome and risk factors of acute renal failure in a surgical population with or without preoperative renal dysfunction. Observational study. Intensive care unit at a University Hospital. Five thousand sixty-eight consecutive adult patients who underwent cardiac surgery with cardiopulmonary bypass. Perioperative variables measured were age, sex, basic pathology, preoperative renal impairment defined as creatinine >1.4 mg/dL, ventricular dysfunction, preoperative neurologic event, chronic obstructive pulmonary disease, diabetes, type of surgery, use of intra-aortic balloon pump (IABP), cardiopulmonary bypass (CPB) duration, redo or emergency surgery, hemorrhage, blood transfusion, surgical revisions, and postoperative complications. Acute renal failure (100% creatinine increase) developed in 171 (3.4%) patients, whereas 94 patients (1.9% of the population) had renal replacement therapy. Hospital mortality was 40.9% in patients with acute renal failure and increased to 63.8% when renal replacement therapy was requested. Sex, age, emergency surgery, low ejection fraction, IABP device, redo, diabetes, mitral valve surgery, CPB duration, and preoperative renal disease were independently associated with acute renal failur...Continue Reading

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