The incidence of inclusion of the sigmoid colon and small bowel in the planning target volume in radiotherapy for prostate cancer

Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
Gert O De MeerleerWilfried J De Neve

Abstract

In radiotherapy for prostate cancer, the rectum is considered the dose-limiting organ. The incidence of overlap between the sigmoid colon and/or small bowel and the planning target volume (PTV) as well as the dose to sigmoid colon and small bowel were investigated. The CT data of 75 prostate cancer patients were analyzed. The clinical target volume (CTV) consisted of prostate and seminal vesicles. The PTV was defined as a three-dimensional expansion of the CTV with a 10-mm margin in craniocaudal and a 7-mm margin in the other directions. All patients were planned to a mean CTV dose of at least 76 Gy. Minimum CTV dose was set at 70 Gy. Dose inhomogeneity within the CTV was kept between 12% and 17%. Sigmoid colon was defined upward from the level where the rectum turned in a transverse plane. Contrast-filled small bowel was contoured on all slices where it was visible. The presence of sigmoid colon and/or small bowel in close vicinity to or overlapping with the PTV was recorded. For each case, the dose to the sigmoid colon and small bowel was calculated. The PTV was found to overlap with the sigmoid colon in 60% and with the small bowel in 19% of the cases. In these patients, mean maximum dose to the sigmoid colon was 76.2 Gy (5t...Continue Reading

Citations

Nov 12, 2010·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Naoki NakamuraKeiichi Nakagawa
May 23, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·K CzignerM Kásler
Apr 10, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Valérie FonteyneGert De Meerleer
May 6, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Cesare CozzariniFerruccio Fazio
Aug 9, 2007·European Journal of Radiology·Geert M Villeirs, Gert O De Meerleer
Jan 16, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gert O De MeerleerWilfried J De Neve
Jun 21, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Sabine Kathrin MaiFrederik Wenz
May 11, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Nora SundahlValérie Fonteyne
Jun 22, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gert De MeerleerWilfried De Neve

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