The incidence of myasthenia gravis: a systematic literature review

Neuroepidemiology
Anita McGroganCorinne S de Vries

Abstract

A systematic review of literature published between 1980 and 2007, on the incidence of myasthenia gravis, was undertaken. All relevant papers found through searches of Medline, Embase and Science Direct were critically appraised and an assessment was made of the reliability of the reported incidence data. Thirty-one studies were included in the review, the majority of which investigated populations in Europe. The incidence rates reported were between 3.0 and 30.0/1,000,000/year. However, it is thought that the rates at the upper end of this range, reported by the prospective studies, provided the most accurate estimates. Overall, incidence rates have increased over time owing to a greater awareness of the disease and improved methods of diagnosis. The most accurate estimate of incidence of myasthenia gravis was around 30/ 1,000,000/year. The incidence in children and adolescents aged 0-19 years was found to be between 1.0 and 5.0/ 1,000,000/year. The rates presented in this review are likely to be an underestimate of the true incidence rates, as mild cases will have been missed and cases in the elderly will have been misdiagnosed.

Citations

Jul 14, 2010·Journal of Neurology·I CasettaE Granieri
Oct 12, 2010·Current Neurology and Neuroscience Reports·Vikas Kumar, Henry J Kaminski
Jun 27, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Pavan M PatilSeema P Patil
Oct 13, 2011·Seminars in Respiratory and Critical Care Medicine·Rob Mac SweeneyMichael A Matthay
Mar 1, 2012·Journal of Clinical Neuromuscular Disease·Chad HeatwoleKatia Noyes
Apr 4, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M GattellariJ M Worthington
Jun 5, 2010·Neuroepidemiology·Chien-Hsu Lai, Hung-Fu Tseng
Jul 16, 2011·Neuroepidemiology·Fabrizio PallaverDomenico Marco Bonifati
Mar 2, 2012·Neuroepidemiology·Cristina MontomoliVittorio E Cosi
May 30, 2014·Journal of Clinical Neuromuscular Disease·Nicholas J Silvestri, Gil I Wolfe
Jan 15, 2014·Seminars in Arthritis and Rheumatism·Julie J PaikAndrew L Mammen
Oct 19, 2011·Autoimmune Diseases·Nils Erik GilhusJohan A Aarli
Mar 4, 2014·Clinical Radiology·A M Priola, S M Priola
Nov 7, 2012·Wiener klinische Wochenschrift·Hakan CetinFritz Zimprich
Jun 29, 2010·Current Opinion in Neurology·Amelia Evoli
Jun 3, 2015·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Jason H PeragalloBeau B Bruce
Sep 2, 2011·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·S Christopher JonesRobert M Boucher
Sep 12, 2015·Muscle & Nerve·Jumana T AlshaikhHenry J Kaminski
Apr 29, 2015·Muscle & Nerve·Julie S HansenHenning Andersen
Aug 14, 2012·Pediatric Neurology·Roshan KoulReem Abdwani
Nov 7, 2015·Current Opinion in Anaesthesiology·Zerrin Sungur, Mert Sentürk
Jul 2, 2014·Acta Neurologica Scandinavica·P Joensen
Mar 5, 2014·Acta Neurologica Scandinavica. Supplementum·J B AndersenN E Gilhus
Aug 5, 2014·Muscle & Nerve·Hani T S Benamer, Amin Bredan
Sep 23, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Marlies KeijzersJos Maessen
Feb 11, 2015·Pediatric Neurology·Mitsuo MotobayashiKenichi Koike
Mar 18, 2015·Experimental and Therapeutic Medicine·Zhi-Xiao YangHui Xiong
Mar 2, 2016·Muscle & Nerve·António Costa BragaJorge Braga
Aug 18, 2016·Acta neurologica Belgica·Athena Alipour-FazMaryam Peyvandi
Feb 26, 2016·Muscle & Nerve·Lotte Vinge, Henning Andersen
Sep 27, 2016·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·T H PopperudE Kerty
Jun 3, 2016·Muscle & Nerve·Jintana B AndersenDonald B Sanders
Feb 28, 2017·Muscle & Nerve·Jacklyn O OmorodionHenry J Kaminski
Jun 20, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Anca Maria Panaitescu, Kypros Nicolaides
Sep 7, 2017·Muscle & Nerve·Coline BarraudBrigitte Chabrol
Sep 8, 2017·Muscle & Nerve·Sivesh K KamarajahArulmaran Sivaguru

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