The incidence of severe chronic ileitis after abdominal and/or pelvic external irradiation with high energy photon beams

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
N DalyM Delannes

Abstract

The authors report a 7.9% incidence of late severe ileal complications after abdominal and/or pelvic external radiation therapy in 188 consecutive patients. All treatments were performed using 25 MV photon beams, with AP-PA field technique, a daily dose of 1.8-2 Gy, 5 times a week. One hundred and two (54.3%) patients were given whole pelvic irradiation up to 45-55 Gy without a boost, 64 patients (34%) received boost doses on limited volumes up to 60-65 Gy. The analysis of factors which could be useful in predicting a high risk of severe ileal sequellae, has shown that the main factor was the past history of previous laparotomy. Thus, the incidence of chronic ileitis in patients who have never been laparotomized in the past and who were treated by radiotherapy alone, was 2.2% (2/97); in contrast patients with previous abdominal surgery whatever its purpose, showed in 13/91 cases (14.3%) severe ileal complications (p less than 0.05). In addition, the risk of chronic ileitis increases with the number of previous laparotomies irrespective of delay or purpose: 10.1% after one laparotomy, 22.2% after two and 50% after three or more laparotomies. The influence of these data on the planning of abdominal and/or pelvic external irradiat...Continue Reading

References

Dec 1, 1986·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·B MaciejewskiH R Withers
Oct 1, 1973·The British Journal of Surgery·J M Wellwood, B T Jackson
Mar 1, 1983·International Journal of Radiation Oncology, Biology, Physics·A D HambergerG H Fletcher

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Citations

Jul 17, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Oliver KoelblMichael Flentje
Aug 5, 2000·International Journal of Radiation Oncology, Biology, Physics·I BarillotJ P Brenier
Sep 25, 2001·International Journal of Radiation Oncology, Biology, Physics·C CapirciG Mandoliti
Jul 1, 1999·International Journal of Radiation Oncology, Biology, Physics·C A PerezJ Williamson
Mar 13, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P ScallietP Lambin
Oct 20, 2000·American Journal of Clinical Oncology·T WasilS Rush
Apr 16, 1998·The British Journal of Radiology·J W Hopewell
Sep 1, 1991·International Journal of Radiation Oncology, Biology, Physics·C A PerezJ Williamson
Nov 10, 2009·Clinical Oncology : a Journal of the Royal College of Radiologists·V S TheisS Lal
Feb 7, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Jennifer J ArthurAmy F Pruitt
Apr 21, 2011·Magyar sebészet·Dániel TeknösFerenc Jakab
Jun 30, 2011·Orvosi hetilap·Zsolt BaranyaiDániel Teknos
Mar 1, 1991·Clinical Oncology : a Journal of the Royal College of Radiologists·B JeremicL J Mijatovic
Oct 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J M BachaudG S Montana
Jun 26, 2004·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·M FirouzmandP Maingon
Jan 1, 1992·World Journal of Surgery·F IzarN Daly
Apr 17, 2002·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Christine R AndersonSusan M LaRue
Jun 1, 2021·Curēus·Artsiom KlimkoElena M Ionescu

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