Feb 1, 1977

The incidence of sister chromatid exchanges in cultured human lymphocytes

Mutation Research
W F Morgan, P E Crossen

Abstract

The incidence of sister chromatid exchanges (SCE) in cultured human lymphocytes from 50 normal individuals was studied using the BUdR-Giemsa technique. The mean SCE frequency per metaphase was 7.9 with a standard deviation of 1.36 and a range of 1-21. The incidence of exchanges was not influenced by the age of the donor nor did the exchange rate differ between sexes. The results of this study are compared with those of previous reports and reasons for the wide variation between results discussed.

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Mentioned in this Paper

Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Sister Chromatid Exchange
Mitotic Metaphase
Lymphoid Cells
Metaphase
Cell Division Phases
Chromatids
Specimen Type - Lymphocytes
Bromodeoxyuridine
Karyotype Determination Procedure

About this Paper

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