The incidence of tuberculosis among adolescents and young adults: a global estimate

The European Respiratory Journal
Kathryn J SnowStephen M Graham

Abstract

Historical data show that the risk of tuberculosis increases dramatically during adolescence, and young people face unique challenges in terms of case detection and effective treatment. However, little is known about the burden of tuberculosis among young people in the modern era. This study aimed to provide the first estimates of the global and regional incidence of tuberculosis among young people aged 10-24 years.Using the World Health Organization (WHO) database of tuberculosis notifications for 2012, we estimated the burden of tuberculosis among young people by WHO region. Adjustments were made for incomplete age disaggregation and underreporting, using supplementary data from several countries representing diverse tuberculosis epidemics.We estimate that 1.78 million (uncertainty interval (UI) 1.23-3.00 million) young people developed tuberculosis in 2012, accounting for 17% of all new tuberculosis cases globally. Young people in the WHO South East Asian Region (721 000, UI 473 000-1.35 million) and the WHO African Region (534 000, UI 359 000-912 000) experienced the greatest number of tuberculosis episodes.Young people suffer a considerable burden of tuberculosis. Age-specific burden of disease estimation for this age grou...Continue Reading

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Citations

Sep 5, 2018·Transboundary and Emerging Diseases·Petra ČernáDanièlle A Gunn-Moore
Feb 23, 2018·The European Respiratory Journal·Alberto L García-BasteiroGiovanni Battista Migliori
May 3, 2019·The European Respiratory Journal·Ying-Ying ChenWei-Juin Su
Nov 14, 2019·Cellular and Molecular Life Sciences : CMLS·Qiyao ChaiCui Hua Liu
Sep 24, 2020·Expert Review of Respiratory Medicine·James A SeddonH Simon Schaaf
Dec 12, 2018·International Journal of Mycobacteriology·Rini Savitri DaulayHeda Melinda Nataprawira
Sep 24, 2020·ERJ Open Research·Silvia S ChiangHelen E Jenkins
Jun 6, 2019·The European Respiratory Journal·Yayehirad A MelsewJames M Trauer
Jun 30, 2019·The European Respiratory Journal·Kathryn J SnowStephen M Graham
Nov 6, 2018·Tropical Medicine and Infectious Disease·Justin T DenholmRichard E Chaisson
Sep 23, 2020·The American Journal of Tropical Medicine and Hygiene·Marcia C B de OliveiraAfrânio L Kritski
Nov 23, 2019·The Lancet Child & Adolescent Health·Kathryn J SnowKatharina Kranzer
Mar 18, 2021·International Journal of Biometeorology·Bijay MaharjanYing Zhang
Feb 4, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Karen du PreezAnneke C Hesseling
Apr 30, 2021·International Journal of Adolescent Medicine and Health·Ufuoma AduhChukwuma Anyaike
Aug 28, 2021·Tropical Medicine and Infectious Disease·Katherine M LaycockAndrew P Steenhoff
Sep 19, 2019·Lancet·Anja ReuterJennifer Furin
Mar 12, 2021·Pediatrics·Muhammad OsmanAnneke C Hesseling

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