PMID: 9176570Mar 1, 1997Paper

The increasing burden of disease in Bangladeshi children due to Haemophilus influenzae type b meningitis

Annals of Tropical Paediatrics
S K SahaT Nagatake

Abstract

A laboratory-based study of diagnosed bacterial meningitis in the national paediatric hospital identified 852 cases of meningitis in the 8-year period 1987-1994. There were 587 culture-positive cases, of which Haemophilus influenzae (47%) and Streptococcus pneumoniae (32%) accounted for 80%. H. influenzae showed a remarkable increase of 700% during the study period. Most of the H. influenzae cases (90%) occurred in the 1st 2 years of life. Analysis of culture-negative specimens by antigen detection in the last 2 years also revealed the predominance of H. influenzae (71.4%) and S. pneumoniae (22.4%). Typing of H. influenzae isolates during this time showed that 98% of the strains were type b. This retrospective hospital-based study indicated a pronounced increase in the incidence of H. influenzae meningitis and strongly supports the need for large-scale Hib vaccination for young children. However, such nationwide intervention will probably need to be based on a prospective on a prospective and population-based surveillance of H. influenzae infections.

References

Sep 1, 1973·The Journal of Infectious Diseases·D W FraserR A Feldman
Sep 16, 1971·The New England Journal of Medicine·R H Michaels
Jul 22, 1961·The Medical Journal of Australia·G M KNEEBONE

❮ Previous
Next ❯

Citations

Mar 7, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·UNKNOWN Invasive Bacterial Infections Surveillance (IBIS) Group of the International Clinical Epidemiology Network
Jan 18, 2003·Annals of Tropical Paediatrics·Sunit C SinghiN K Ganguly
Nov 30, 2006·Annals of Tropical Paediatrics·Samir K SahaMathuram Santosham
Apr 16, 2011·Epidemiology and Infection·A VyseM Soriano-Gabarro
Dec 16, 2000·American Journal of Epidemiology·M S DurkinS S Zaman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Meningitis (ASM)

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Meningitis

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.