The increasing rates of acute interstitial nephritis in Australia: a single centre case series

BMC Nephrology
Gregory J WilsonAndrew J Mallett

Abstract

The Australian Institute of Health and Welfare's first report into acute kidney injury demonstrated a significant increase in the incidence of acute-tubulo interstitial nephritis, the ICD-10 code representing both acute interstitial nephritis and pyelonephritis, in women aged less than 55 years. In contrast, recent case series have reported rising rates of drug induced acute interstitial nephritis predominantly among elderly patients. Due to several limitations with the Australian Institute of Health and Welfare report, this new trend requires further investigation to determine if rates of acute interstitial nephritis are truly increasing among younger Australian women. Patients who underwent a renal biopsy at a single center from 2000 to 2015 were reviewed and those with biopsy confirmed acute interstitial nephritis were selected. Cause of acute interstitial nephritis, patient demographics, co-morbidities and renal indices for these patients when available were recorded and compared. Eight hundred ninety-eight patients who underwent renal biopsy from 2000 to 2015 were reviewed and 40 patients were identified with biopsy confirmed acute interstitial nephritis. The rate of acute interstitial nephritis increased significantly ove...Continue Reading

References

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Citations

Jul 8, 2020·International Journal of Molecular Sciences·Laura Martinez ValenzuelaJuan Torras
Jul 11, 2020·KI Reports·Benjamin LazarusRebecca Pellicano

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

R
R Foundation for Statistical Computing

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