The index of microcirculatory resistance measured acutely predicts the extent and severity of myocardial infarction in patients with ST-segment elevation myocardial infarction.

JACC. Cardiovascular Interventions
Ross McGeochKeith G Oldroyd

Abstract

This study investigated the relationship between the index of microcirculatory resistance (IMR) with myocardial injury and microvascular obstruction (MVO) assessed by contrast-enhanced cardiac magnetic resonance (ceCMR) imaging in a broad range of ST-segment elevation myocardial infarction (STEMI) patients undergoing emergency percutaneous coronary intervention (PCI). Contrast-enhanced cardiac magnetic resonance imaging is the gold standard for assessment of microvascular obstruction (MVO), left ventricular (LV) ejection fraction, and infarct volumes in ST-segment elevation myocardial infarction (STEMI). However, ceCMR is not available acutely. The index of microcirculatory resistance is a simple invasive measure of microvascular function available at the time of emergency PCI. We investigated the relationship between IMR with myocardial injury and MVO assessed by ceCMR in STEMI patients undergoing emergency PCI. Fifty-seven patients with STEMI were included and 53 (93%) and 47 (82%) patients had complete ceCMR scans 2 days and 3 months following MI, respectively. Microvascular obstruction was defined as a dark core of hypoenhancement within the area of hyperenhanced infarct tissue 10 to 15 min following intravenous gadolinium ...Continue Reading

References

Jun 25, 2003·Circulation·William F FearonAlan C Yeung
Feb 20, 2004·European Heart Journal·Emanuele BarbatoUNKNOWN Week 25 study group
Oct 7, 2004·Circulation·Wilbert AarnoudseNico H J Pijls
Jan 16, 2007·European Heart Journal·Colin BerryKeith G Oldroyd
Feb 23, 2007·The New England Journal of Medicine·Paolo G Camici, Filippo Crea
Mar 10, 2007·European Heart Journal·Amir LermanBernard J Gersh
Jun 1, 2007·The New England Journal of Medicine·J Roberto Duran, George Taffet
Feb 2, 2008·Journal of the American College of Cardiology·William F FearonAlan C Yeung
Jul 18, 2009·Journal of the American College of Cardiology·Giampaolo NiccoliFilippo Crea

❮ Previous
Next ❯

Citations

Apr 2, 2011·Journal of Cardiovascular Translational Research·Parham EshtehardiHabib Samady
Feb 25, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Melissa LeungDominic Y Leung
Dec 21, 2013·Journal of the American College of Cardiology·Christopher A MillerMatthias Schmitt
Aug 30, 2011·The American Journal of Cardiology·Alberto Ranieri De CaterinaFilippo Crea
Jun 30, 2011·Journal of Molecular and Cellular Cardiology·Bryan G Schwartz, Robert A Kloner
Jan 25, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Atsushi HirohataTohru Ohe
Jan 25, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Seong-Ill WooSoo-Hyeon Kim
Mar 11, 2016·Nature Reviews. Cardiology·Karim D Mahmoud, Felix Zijlstra
Jul 22, 2015·International Journal of Cardiology·Jamie LaylandKeith Oldroyd
Dec 3, 2014·Journal of the American College of Cardiology·Gilles Rioufol, Gérard Finet
Dec 25, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Massoud A Leesar
Jan 19, 2016·Global Cardiology Science & Practice·Jan Bogaert, Ingo Eitel
Aug 8, 2015·Coronary Artery Disease·Gonzalo J MartínezMartin K C Ng
Jun 19, 2015·Coronary Artery Disease·Stephen P HooleNick E J West
May 3, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Doyeon HwangBon-Kwon Koo
Mar 1, 2014·American Heart Journal·Robin HofmannTomas Jernberg
Oct 18, 2016·Journal of Comparative Effectiveness Research·Nadeem AhmedColin Berry
Oct 11, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Sang-Don ParkKeum-Soo Park
Nov 21, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Giovanni Luigi De MariaAdrian P Banning
Nov 30, 2016·Journal of Cardiovascular Medicine·Riccardo GorlaJorge A Salerno-Uriarte

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.