The inducible form of heat shock protein 70 in the serum, colon and small intestine of the pig: comparison to conventional stress markers

The Veterinary Journal
K Sepponen, A R Pösö

Abstract

Modern rearing conditions may cause stress to pigs. At the cellular level all animals respond to stress by synthesizing heat shock proteins (HSP), which protect cells from injury. The objective of this study was to examine the concentrations of stress-inducible HSP72 in porcine small intestine and colon, known to be stress sensitive tissues, and to compare the findings with HSP72 concentrations in serum and with conventional markers of stress, namely blood lactate and serum cortisol, glucose, free fatty acids and acute phase proteins. HSP72 in the colon correlated with serum HSP72 but there was a negative correlation with carcass weight (growth). The results suggest that the colon may be a significant source of serum HSP72, the concentration of which may reflect changes in the permeability of intestinal epithelium due to stressors, such as transport and handling.

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Citations

May 10, 2008·Cell Stress & Chaperones·Endong BaoJ Hartung
Jun 24, 2011·European Journal of Nutrition·M N OrsenigoM Tosco
Mar 29, 2013·Animal : an International Journal of Animal Bioscience·E NegratoL Bonfanti
Nov 1, 2013·Acta Veterinaria Scandinavica·Anna ValrosA Reeta Pösö
Feb 18, 2016·Nutrition Reviews·Marie-Edith Arnal, Jean-Paul Lallès
Jun 22, 2007·The Veterinary Journal·Francisco J PallarésJosé J Cerón
Apr 6, 2013·BMC Veterinary Research·Xin WuZeyuan Deng
Jan 1, 2010·Cognitive Science·Christopher G Lucas, Thomas L Griffiths
Jul 20, 2019·Antioxidants·Chiara SironiCristina Porta

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