PMID: 1203210Dec 1, 1975Paper

The influence of abnormal glucose tolerance (hyperglycaemia and hypoglycaemia) on pregnancy outcome when oestriol excretion is subnormal

British Journal of Obstetrics and Gynaecology
D A Abell, N A Beischer

Abstract

Subnormal urinary oestriol excretion was present in 611 (13.9 per cent) of 4403 consecutive patients in whom a glucose tolerance test had been performed and urinary oestriol excretion measured during the third trimester of pregnancy. Hypoglycaemia (less than 5th centile) had a significant association with subnormal oestriol excretion. The perinatal mortality rate was significantly higher in the presence of abnormal glucose tolerance when oestriol excretion was low. Normoglycaemia was associated with a perinatal mortality rate of 1.7 per cent when oestriol excretion was persistently low, whereas in the presence of hyperglycaemia (greater than 95th centile) the perinatal mortality rate was 12.5 per cent (P less than 0.01) and when there was hypoglycaemia the rate was 14.8 per cent (P less than 0.001). Small-fordates babies occurred in 46.3 per cent of pregnancies complicated by hypoglycaemia and persistently subnormal urinary oestriol excretion. The advantage of routine urinary oestriol assay and glucose tolerance testing in pregnancy is emphasized.

References

Apr 1, 1973·Obstetrical & Gynecological Survey·D R Ostergard
May 1, 1972·Obstetrical & Gynecological Survey·N A Beischer, J B Brown
May 1, 1972·The Australian & New Zealand Journal of Obstetrics & Gynaecology·J H EvansJ B Brown
Jan 1, 1972·Diabetes·C B KahnD Younger
Jul 15, 1972·American Journal of Obstetrics and Gynecology·N A Beischer, E F O'Sullivan
Jan 1, 1974·Acta Obstetricia Et Gynecologica Scandinavica·A Victor
Jun 8, 1974·The Medical Journal of Australia·C A Macafee, N A Beischer
Jan 15, 1972·American Journal of Obstetrics and Gynecology·K Karlsson, I Kjellmer
Mar 15, 1970·American Journal of Obstetrics and Gynecology·M E RivlinG V Anderson
Oct 1, 1970·American Journal of Obstetrics and Gynecology·W OhL Hohenauer
Oct 1, 1968·The Journal of Obstetrics and Gynaecology of the British Commonwealth·N A BeischerM A Smith
Aug 1, 1967·American Journal of Obstetrics and Gynecology·P PatersonC Wood

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Citations

Mar 1, 1979·British Journal of Obstetrics and Gynaecology·D A Abell
Jan 29, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nir MelamedYariv Yogev
May 1, 1980·The Australian & New Zealand Journal of Obstetrics & Gynaecology·D A Abell, N A Beischer

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