PMID: 1201133Nov 1, 1975Paper

The influence of allopurinol on renal function in gout

Arthritis and Rheumatism
W G BrineyC J Smyth

Abstract

Our data demonstrate that adequate control of uric acid production and serum acid concentration in primary gout arrests further deterioration of renal function and in some instances permits subsequent improvement in renal hemodynamic function even when renal impairment is clearly established. In considering the nature of the lesions of urate nephropathy, our study suggests that control of serum uric acid with drug therapy before renal involvement is apparent might prevent or significantly delay the morbidity and mortality of this complication of primary gout.

References

May 1, 1972·Arthritis and Rheumatism·S L Wallace
Feb 1, 1966·Annals of Internal Medicine·R W RundlesH R Silberman
Nov 1, 1966·Annals of the Rheumatic Diseases·F DelbarreA de Gery
Jan 1, 1970·Annals of the Rheumatic Diseases·G D Kersley
Nov 1, 1966·Annals of the Rheumatic Diseases·M A OgryzloJ B Houpt
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Mar 1, 1967·Annals of the Rheumatic Diseases·J D WilsonJ D North
May 1, 1950·Proceedings of the Society for Experimental Biology and Medicine·G E SCHREINER
May 1, 1945·The Journal of Clinical Investigation·H W SmithM Graber
Nov 1, 1966·Annals of the Rheumatic Diseases·O Savage

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Citations

Jun 28, 1979·The New England Journal of Medicine·G R Boss, J E Seegmiller
Nov 29, 1979·The New England Journal of Medicine·J H Talbott
Feb 26, 1981·The New England Journal of Medicine·V BatumanR P Wedeen
Feb 1, 1982·Annals of the Rheumatic Diseases·T GibsonH A Simmonds
Oct 18, 2011·Seminars in Nephrology·Richard J JohnsonLaura Gabriela Sánchez-Lozada
Jul 1, 1979·The American Journal of Medicine·W J Fessel
Mar 17, 2004·Arthritis and Rheumatism·Ted R MikulsKenneth G Saag
Apr 22, 2005·Journal of the American Society of Nephrology : JASN·Richard J JohnsonJaime Herrera Acosta
Feb 25, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Xiao-Jing LouSu-Hong Chen

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