The influence of anaesthesia and surgery on the circadian rhythm of melatonin

Acta Anaesthesiologica Scandinavica
J KärkeläM Pasanen

Abstract

Operations are typically associated with sleep and other circadian rhythm disturbances. The present study was set up to evaluate the influence of spinal and general anaesthesia associated with knee surgery on the circadian rhythm of melatonin, which has sleep inducing properties. Previously this context has been studied only in some invasive operations and it might be that general anaesthesia induces more disturbances on circadian rhythm of melatonin than operations done with patients awake. The circadian secretion pattern of melatonin was monitored during the pre- and postoperative evenings, nights and mornings to clarify possible anaesthesia/surgery-induced changes in the nocturnal secretion of melatonin and in the phase of the melatonin rhythm. The study included 20 patients scheduled for minor orthopaedic operations. The patients were randomised to receive either spinal or general anaesthesia. Melatonin was measured from evening and morning saliva samples radioimmunologically. The nocturnal urine before and after surgery was radioimmunologically examined for 6-hydroxymelatonin sulphate. Melatonin secretion evaluated from the saliva samples was significantly diminished during the first postoperative evening as compared with ...Continue Reading

References

May 11, 1991·Lancet·M DahlitzJ D Parkes
Dec 1, 1991·Anesthesiology·D I SesslerJ McGuire
Aug 1, 1991·The Journal of Clinical Endocrinology and Metabolism·N E Rosenthal
Jan 1, 1989·Life Sciences·I M McIntyreS M Armstrong
Jan 1, 1985·Annals of the New York Academy of Sciences·G A Groos, J H Meijer
Jul 1, 1985·Acta Physiologica Scandinavica·O Vakkuri
Mar 1, 1967·American Journal of Public Health and the Nation's Health·T F WilliamsE V Ellis
Aug 1, 1993·Journal of Pineal Research·D Dawson, N Encel
Jan 1, 1993·Psychoneuroendocrinology·B R Grad, R Rozencwaig
Nov 1, 1995·Clinical Physiology·T PartonenC Lamberg-Allardt
Nov 5, 1997·Journal of Biological Rhythms·A VoultsiosD Dawson
Sep 24, 1998·Journal of Pineal Research·G Jean-LouisF Zizi
Oct 1, 1998·Journal of Pineal Research·S NishimuraI Yoshiya
Nov 11, 1998·Acta Anaesthesiologica Scandinavica·A ReberM Schneider
Sep 2, 1999·Biochemical and Biophysical Research Communications·B ChetsawangP Govitrapong

❮ Previous
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Citations

Sep 4, 2007·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Dominique ChassardEmmanuel Boselli
Feb 16, 2006·Intensive Care Medicine·Richard S Bourne, Gary H Mills
Apr 28, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Etienne ChalletLaure Pain
May 11, 2000·Pediatrics International : Official Journal of the Japan Pediatric Society·S YokotaM Mori
Sep 25, 2004·Biological Research for Nursing·Marion GoodXiaomei Cong
Sep 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Hikmet Yilmaz, Ihsan Iskesen
Sep 10, 2013·Saudi Journal of Anaesthesia·Souvik MaitraPuneet Khanna
Jul 5, 2013·Indian Journal of Anaesthesia·Madhuri S Kurdi, Tushar Patel
Dec 21, 2006·World Journal of Surgery·Ismail GögenurJacob Rosenberg
Nov 14, 2008·Chronobiology International·Garance DispersynYvan Touitou
Oct 25, 2006·Brain Injury : [BI]·Thomas PaparrigopoulosXenia Geronikola
Jul 6, 2010·Annales Françaises D'anesthèsie Et De Rèanimation·G DispersynL Pain
Feb 12, 2008·The Journal of Surgical Research·Bülent KücükakinJacob Rosenberg
Mar 24, 2007·Journal of Clinical Anesthesia·Argyro FassoulakiSophia Markantonis
Sep 9, 2005·Acta Anaesthesiologica Scandinavica·L S RasmussenUNKNOWN ISPOCD2 Investigators
Jan 3, 2007·Journal of Pineal Research·Mohamed NaguibPeter A Goldstein
Aug 19, 2007·Acta Anaesthesiologica Scandinavica·I GögenurJ Rosenberg
Apr 30, 2013·Basic & Clinical Pharmacology & Toxicology·Yajie LiuXiangyang Guo
Sep 10, 2010·Acta Anaesthesiologica Scandinavica·T KvaslerudI Gögenur
Apr 28, 2005·European Journal of Anaesthesiology·A SamarkandiA Albassam
Jun 1, 2010·Acta Physiologica Hungarica·P KanizsaiZ Szelényi
Apr 17, 2015·Critical Care : the Official Journal of the Critical Care Forum·Rong-Fang HuYou-Hua Zhang
Sep 1, 2012·General and Comparative Endocrinology·Aneta PiesiewiczPawel Marek Majewski
Jan 26, 2010·Anesthesiology·Garance DispersynYvan Touitou
Mar 26, 2008·Anesthesiology·Christopher P BonafideArthur J Cronin
Jul 6, 2016·The Kaohsiung Journal of Medical Sciences·Elvan OcmenAli N Gokmen
Dec 5, 2015·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Hege Andersen AmofahUNKNOWN CARDELIR Investigators
Oct 9, 2014·Seminars in Cardiothoracic and Vascular Anesthesia·Jason BrainardTobias Eckle
Mar 6, 2018·Southern Medical Journal·Khaled DajaniKierstin Lund
Jan 24, 2004·Anesthesiology·Dominique Chassard, Bernard Bruguerolle
May 5, 2007·Current Opinion in Anaesthesiology·Dominique ChassardEmmanuel Boselli
Dec 24, 2018·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Linda FreitagVincent A Stadelmann
Mar 21, 2009·Anesthesia and Analgesia·Mohamed Naguib, Peter A Goldstein
Apr 14, 2011·Anaesthesia and Intensive Care·J Jarratt

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