Abstract
The incidence of cardiovascular and neurovascular diseases has been increasing with the aging of the population, and antiplatelet drugs (APDs) are more frequently used than in the past. With the average age of spinal surgery patients also increasing, there has been a great concern on the adverse effects of APD on spine surgery. To our knowledge, though there have been many studies on this issue, their results are conflicting. In this study, we aimed to determine the influence of APDs on spine surgery in terms of intraoperative bleeding and postoperative spinal epidural hematoma complication. Patients who underwent posterior thoracolumbar decompression and instrumentation at our institution were reviewed. There were 34 APD takers (APDT group). Seventy-nine non-APD takers (NAPDT group) were selected as a control group in consideration of demographic and surgical factors. There were two primary endpoints of this study: the amount of bleeding per 10 minutes and cauda equina compression by epidural hematoma measured at the cross-sectional area of the thecal sac in the maximal compression site on the axial T2 magnetic resonance imaging scans taken on day 7. Both groups were homogeneous regarding age and sex (demographic factors), the...Continue Reading
References
Aug 25, 2001·The New England Journal of Medicine·S YusufUNKNOWN Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators
Sep 25, 2001·Deutsche medizinische Wochenschrift·J WeberA Spring
Sep 6, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Marcus C KorinthMartin R Weinzierl
Nov 13, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·C M Samama, W-H Geerts
Dec 25, 2009·Circulation. Cardiovascular Interventions·Andrew C Y ToMark W I Webster
Jun 18, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Massimo A LeonardiK Min
Nov 10, 2010·Seminars in Cardiothoracic and Vascular Anesthesia·Tzong-Huei Chen, Robina Matyal
May 18, 2013·Spine·Jin Hoon ParkSung Woo Roh
Dec 18, 2013·The American Journal of Medicine·Michael J Wahl
Jul 18, 2014·Current Therapeutic Research, Clinical and Experimental·Jeonghun LeeMin Su Hyon
Mar 12, 2015·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jehuda SolemanAli-Reza Fathi
Jun 2, 2015·Spine·Jason M CuellarJohn A Bendo
Jun 28, 2016·Gastrointestinal Endoscopy·Diogo LibânioMário Dinis-Ribeiro
Nov 23, 2016·Journal of Clinical Anesthesia·Nathaniel R SmilowitzJeffrey S Berger