The influence of buscopan on adverse reactions to intravascular contrast media

The British Journal of Radiology
S SharmaR K Goulatia


We have analysed the ability of prior intravenous Buscopan (hyoscine butylbromide) injection to influence the incidence and severity of adverse reactions to intravascularly administered, iodinated, ionic contrast medium in 258 consecutive digital subtraction angiographic (DSA) examinations. Adverse reactions were seen in 7.9% of the intravenous and 2.4% of the intra-arterial DSA examinations. The incidence of adverse reactions with and without prior Buscopan injection during intravenous DSA examinations was 8.2% and 7.1%, respectively and during intra-arterial DSA examinations was 5.6% and 1.5%, respectively. This difference is not statistically significant (chi 2-test). We conclude that prior intravenous injection of Buscopan has no influence on the incidence or severity of adverse reactions to intravascular contrast media.


Jul 1, 1988·The British Journal of Radiology·G G Hartnell, A P Hemingway
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Nov 1, 1970·Investigative Radiology·G Ansell
May 1, 1971·Acta Radiologica: Diagnosis·E BoijsenT Hallböök
Apr 1, 1971·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·M N Coel, E C Lasser
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Sep 1, 1983·The British Journal of Radiology·P Dawson, D Edgerton
Nov 1, 1980·Investigative Radiology·G AnsellL Couch

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May 25, 2005·Fundamental & Clinical Pharmacology·Jean-Marc IdéeClaire Corot

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